NCT03409224终止不适用
Differences in Immunologic Response to Cryoablation Versus Radiofrequency Ablation in the Treatment of Renal Cell Carcinoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 53
- 主要终点
- Immune Response to Cryoablation, RFA and Laparoscopic Partial Nephrectomy
研究概览
简要总结
The purpose of this study is to compare changes in the body's self-defense (immune response) after two different treatments for small kidney tumors: 1) Cryoablation (freezing) therapy in which the tumor and a margin of normal kidney tissue are frozen and thawed twice with a needle probe and 2) radiofrequency ablation (RFA) in which radiofrequency energy delivered through a needle probe is used to heat tissue and thereby destroy a tumor.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •You are eligible to participate in this study if you are an adult (older than 18 years)
- •Diagnosed with renal cell cancer 1-3 centimeters in size on the CT scan.
排除标准
- •You are not eligible to participate in this study if you are immune compromised (chemotherapy,corticosteroid use, HIV [as documented in your medical record], etc.)
- •Have an autoimmune disorders (Rheumatoid arthritis, Crohn's disease, etc)
- •Have a tumor larger than 4 cm
- •Are pregnant.
结局指标
主要结局
Immune Response to Cryoablation, RFA and Laparoscopic Partial Nephrectomy
时间窗: 4 years
The number of leukocytes found in the tissues cryoablation, radiofrequency ablation, or laparoscopic partial nephrectomy (control)
次要结局
未报告次要终点
研究者
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