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Comparison of the effects of Ketamine-Metoclopramide and Acetaminophen-Metoclopramide in deep Vitrectomy surgery

Phase 3
Conditions
Vitrectomy.
Disorders of vitreous body
Registration Number
IRCT20150106020588N9
Lead Sponsor
Esfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
68
Inclusion Criteria

Candidate for Vitrectomy surgery
Age 40 to 80 years
ASA class I and II
Informed consent to enter the study

Exclusion Criteria

History for abusing the drugs, alcohol and psychedelics
Known allergy to ketamine, Acetaminophen, and Metoclopramide
History of mental illness and seizures
Pregnancy and breastfeeding
Body Mass Index (BMI) greater than 35
Taking painkillers 24 hours before surgery

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The amount of pain after the operation. Timepoint: Upon entering recovery, 30 minutes, 2 hours, 4 hours, 8 hours, 24 hours after surgery. Method of measurement: Visual Analogue Scale.
Secondary Outcome Measures
NameTimeMethod
Heart Rate. Timepoint: Upon entering recovery, 30 minutes, 2 hours, 4 hours, 8 hours, 24 hours after surgery. Method of measurement: Electrocardiogram.;Blood Pressure. Timepoint: Upon entering recovery, 30 minutes, 2 hours, 4 hours, 8 hours, 24 hours after surgery. Method of measurement: Sphygmomanometer.
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