Comparison of two different anesthetic agents on its influence on changing hemodyanamic and doppler parameters of mitral valve diseased patients posted for valve replacement
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056224
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
.1)Patients with mitral stenosis undergoing elective mitral valve replacement under cardiopulmonary bypass. 2) Age >18 and < 70years
1. Patients not willing to participate in study 2. More than mild mitral regurgitation. 3. Patients with associated aortic, pulmonary and tricuspid valve disease 4. Patients with associated coronary artery disease, severe PAH. 5. Redo-surgeries 6. Emergency surgeries 7. Preoperative inotropic supports. 8. Preoperative intra-aortic balloon pump (IABP) 9. sub-optimal pre-induction and post-induction transthoracic echo images 10. Patients having post balloon mitral valvotomy atrial septal defect or any significant pathology that would affect hemodynamic parameters and echocardiographic profile.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effects of sevoflurane and Propofol induction on the following echocardiographic parameters in MS patients undergoing MVR 1. Mitral valve area (planimetry & continuity equation) 2. Peak velocity 3. Peak and mean gradient 4. Pressure half time (PHT) 5. Deceleration Time (DT) 6. Pulmonary artery systolic pressureTimepoint: 0 and 3 minutes of anesthesia
- Secondary Outcome Measures
Name Time Method 1. To compare the following hemodynamic parameters with Propofol & sevoflurane induction a). Mean arterial pressure(MAP) b). Cardiac output (CO) c). Heart rate ( HR) 2. To compare the Left ventricular & right ventricular function with Propofol & sevoflurane inductionTimepoint: 0 & 3 minutes of anesthesia