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comparison of the effect of two kind of anaesthetic agents on brain physiology in patients undergoing brain tumor removal

Not Applicable
Completed
Conditions
Health Condition 1: D330- Benign neoplasm of brain, supratentorialHealth Condition 2: C710- Malignant neoplasm of cerebrum, except lobes and ventriclesHealth Condition 3: null- PATIENTS WITH SUPRATENTORIAL SPACE OCCUPING LESION (TUMOUR)
Registration Number
CTRI/2016/05/006923
Lead Sponsor
Postgraduate institute of medical education and research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
45
Inclusion Criteria

Patients with supratentorial brain tumor posted for craniotomy and excision

Exclusion Criteria

Patient with Glasgow Coma Scale <15

Patient with Midline shift >5mm in CT scan of brain

Patient having moderate to severe pulmonary obstruction or restriction

Patient having decompensated cardiac disease such as arrhythmias, ischemic or valvular heart disease.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
compare the effect of intravenous (propofol) and inhalational (sevoflurane and desflurane) anaesthetic agents on cerebral hemodynamics in form of SJVO2 in patients undergoing supratentorial brain tumor resectionTimepoint: October 2015 to September 2016
Secondary Outcome Measures
NameTimeMethod
Compare the effect of intravenous (propofol) and inhalational (sevoflurane and desflurane) anaesthetic agents on cerebral haemodynamics in form of arterio-venous oxygen content difference, recovery from anaesthesia in the form of emergence time, tracheal extubation time, recovery time and intraoperative condition of brain <br/ ><br>in patients undergoing supratentorial brain tumor resectionTimepoint: October 2015 to September 2016
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