IRCT20141009019470N105招募中2 期
The comparison between oral modafinil and placebo to accelerate the rate of improvement in the level of consciousness in adult patients with moderate or severe acute traumatic brain injury admitted in intensive care units of Rajaee Trauma Center in 1399-1400
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 314
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 70 years（—）
- 性别
- All
入选标准
- •Patients who have a GCS score between 6 and 12 at the time of initiation of NG tube feeding in the ICU
- •Head AIS score above 3 on the first day of ICU stay, the AIS score of the other parts below 3 on the first day of ICU stay, the consent of the patient's guardian or legal guardian
- •Consent of the patient's guardian or legal guardian
- •Age over 18 years and under 70 years
- •Patients with moderate or severe head injury who are admitted to intensive care
排除标准
- •Severe side effects such as severe agitation or anaphylactic reaction to modafinil
- •Occurrence of seizures
- •Incidence of death or brain death
- •multiple trauma
- •Injury Severity Score less than 20
- •History of psychotropic and brain stimulant drug abuse and alcoholism
- •History of severe liver failure
- •History of seizures
- •History of Anxiety Disorders
- •Cardiac or respiratory recurrence in the first 6 days of hospitalization
研究者
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