Markers of Brain injury study (MOBI)

Not Applicable

Recruiting

• Conditions: Traumatic Brain Injury; Neurological - Other neurological disorders

• Registration Number: ACTRN12612000899842
• Lead Sponsor: eurotrauma research program of WA institute of medical research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Traumatic brain injury requiring Intracranial Pressure Monitoring

Exclusion Criteria

Unlikely to survive the first 24 hours of hospitalisation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glasgow Outcome Score- this is a measure of the qulaity of functional neurological outcome[6 months.]

Secondary Outcome Measures

Name	Time	Method
Plasma and CSF samples will be subjected to GC-MS/ HPLC analysis to determine concentrations of Isoprostanes, Isofurans and Neuroprostanes. We will use satistical methods to examine the correlation between plasma and CSF samples and their predictive utility in terms of outcome.[Over the period of ICP monitoring (up to and including Day 7 of admission)]