Furcation Treatment With L-PRF and aPDT

Not Applicable

Completed

• Conditions: Furcation Defects
• Interventions: Procedure: L-PRF with aPDT; Procedure: L-PRF

• Registration Number: NCT04842188
• Lead Sponsor: Kafrelsheikh University

Brief Summary

To treat grade II periodontally diseased furcation areas Leukocyte-Platelet Rich Fibrin (L-PRF) combined with antimicrobial Photo-Dynamic Therapy (a-PDT) was used.

Detailed Description

randomized, triple-blinded study (patient, clinician and biostatistician). Twenty-four patients with Grade II furcation involvement were recruited in this study.

Control group only received L-PRF, while study group used a combination of L-PRF and aPDT Attachment level, pocket depth, horizontal component and gingival recession, also radiographic Bone depth, width, height and volume were were recorded at baseline and postoperatively after 6 months

Study Timeline

• Study Start: 2020-07-28
• Study First Submitted: 2021-04-08
• Study First Submitted QC: 2021-04-08
• Primary Completion: 2021-04-12
• Study First Posted: 2021-04-13
• Study Completion: 2021-04-30
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-20
• Last Update Posted: 2021-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Grade II furcation involvement
• age range 18- 50 years
• 3 mm or more vertical probing depth

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Exclusion Criteria

• systemic disease
• abnormal clotting and bleeding
• smokers,
• root caries or restoration
• Grade II mobility
• periapical lesions

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
L-PRF with aPDT	L-PRF with aPDT	Leukocyte platelet rich fibrin combined with antibacterial photodynamic therapy in class II furcation
L-PRF	L-PRF	Leukocyte platelet rich fibrin as a sole graft material in class II furcation

Primary Outcome Measures

Name	Time	Method
clinical evaluation of vertical pocket depth VPD	6 months	using periodontal probe in mm
clinical evaluation of gingival recession REC	6 months	using periodontal probe in mm
Clinical evaluation of Vertical clinical attachment level VCAL	6 months	using periodontal probe in mm
clinical evaluation of furcation horizontal component FHC	6 months	using periodontal probe in mm

Trial Locations

Locations (1)

faculty of dentistry, kafrelsheikh University; 🇪🇬 Kafr Ash Shaykh, Egypt