Changing neural processing of olfactory and visual food cues by sensory specific satiety

Completed

• Conditions: overeating; 10003018; overweight

• Registration Number: NL-OMON42333
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

• Gender: female
• Age: from 18 - 35 years
• Handedness: Right dominant hand
• Language: good Dutch reading and writing skills
• BMI: 18.5 <= BMI <= 25 kg/m2
• Health: good general health (subjective)
• Appetite: healthy appetite
• Olfaction: Normosmic (Sniffin* Sticks ID >= 12)

Exclusion Criteria

• Medical background: Having a history of medical or surgical events that may significantly affect the study outcome (affecting tasting, smelling, swallowing), neurological problems (e.g. epilepsy)
• Chronic diseases: Having chronic disorders that can influence the outcome parameters of the study (e.g. thyroid disease, diabetes, kidney disorders)
• Pregnancy: (intention to get) pregnant or breast feeding during the past 6 months
• Medical drug use: use of medication, except for paracetamol and contraceptive medication.
• Mental status: when incompatible with the proper conduct of the study
• Food allergy: allergy or intolerance for the ad libitum products that will be consumed in the study.
• Liking liking < 40 mm on VAS for the ad libitum intake products and for the odours
• Alcohol consumption more than 7 alcoholic drinks per week
• Recreational drug use
• Smoking more than 1 cigarette/cigar/pipe per week
• DEBQ: Dutch Eating Behaviour Questionnaire Restraint score > 2.8
• Weight loss: Reported unexplained weight loss or weight gain of > 5 kg in the two months prior to pre-study screening
• Diet: Reported slimming or medically prescribed diet
• Lack of appetite
• Conviction: Reported vegan, vegetarian or macrobiotic life-style
• Dependent relation: Personnel of Wageningen University, department of Human Nutrition, their partner and their first and second degree relatives
• Other research: Current participation in other research from the Division of Human Nutrition (except for the Eet-Meet-Weet onderzoek)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The difference in event related potentials (obtained with the use of EEG) in<br /><br>response to different food cues (odour/picture; sweet/savoury; high/low energy<br /><br>dense), as well as the difference in ERP before and after sensory specific food<br /><br>intake. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>&Delta; Appetite, measured at two time-points (before and after eating a product) on<br /><br>a visual analogue scale, and the correlation between these differences and<br /><br>differences in ERP responses.</p><br>