The Safety and Adverse Reaction Study of Neonatal to Inhaled Carbon Monoxide
- Conditions
- Miscellaneous Disorders in the Fetus or Newborn
- Interventions
- Other: Inhaled Carbon Monoxide
- Registration Number
- NCT01818843
- Lead Sponsor
- CAN WANG
- Brief Summary
Based on the study about carbon monoxide in human inflammatory and other beneficial physiological function , now we'll be going to research its application in neonates .Phase 1 Study as a foundation for the further test is, the safety and Adverse reaction study of newborn to inhaled CO
- Detailed Description
Previous studies have demonstrated that, carbon monoxide has showed the effectiveness such as in inflammation ,apoptosis as well as relaxation of smooth muscle of the body. Now we have a hypothesis to use carbon monoxide in pulmonary hypertension of the newborns, to observe whether it will decrease pulmonary artery hypertension on newborns. Phase 1 study is ,the safety and Adverse reaction study of newborn to inhaled CO , after this,we can master the application of carbon monoxide dose
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 24
- The newborn whose physiological function is healthy or close to healthy
- Clinical considerations cannot survive or no treatment value of newborn Diagnosis of congenital or hereditary diseases, or children with heart diseaseCentral pulmonary vascular malformations in children
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Safety and Adverse Reaction in CO Inhaled Carbon Monoxide Inhaled Carbon Monoxide
- Primary Outcome Measures
Name Time Method Number of participants with adverse events up to 1 month
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Daping Hospital
🇨🇳ChongQing, Chongqing, China