NCT03963063已完成不适用
Efficacy of Perioperative Goal-directed Fluid Therapy in Preventing Cerebral Desaturation and Postoperative Cognitive Dysfunction After Beach Chair Position Shoulder Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- duration of cerebral desaturation events
研究概览
简要总结
Patients receiving beach chair position shoulder surgery are vulnerable to perioperative cerebral desaturation, which is reported to be a risk factor for postoperative cognitive dysfunction. Investigators design this study to test the efficacy of perioperative goal-directed therapy in preventing cerebral desaturation and postoperative cognitive dysfunction in patients receiving beach chair position shoulder surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients receiving scheduled beach chair position shoulder surgery
排除标准
- •pregnant women
- •patients in intensive care units
- •patients with respiratory failure [forced expiratory volume at one second (FEV1)/ forced vital capacity (FVC) < 70 % and FEV1 < 50%]
- •patients with heart failure(NYHA score =III、IV)
- •patients with chronic kidney disease (eGFR< 60 ml.min-1.1.73m-2)
- •patients with liver failure
- •patients with ongoing infection
- •patients allergic to voluven
结局指标
主要结局
duration of cerebral desaturation events
时间窗: 3 hours
patients will be monitored with bilateral cerebral oxymetry, and investigators will compare the duration of cerebral desaturation events
次要结局
- incidence of cerebral desaturation events(3 hours)
- postoperative cognitive dysfunction assessed by the Taiwan version of questionnaire Qmci(3 days)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Assessing Cerebral Blood Flow Autoregulation During Surgery in the Head-up PositionShouldersurgeryNCT01225185Johns Hopkins University240
Unknown
不适用
Sequential Compression Device (SCD) for Stabilizing Hemodynamics in the Beach Chair PositionHypotensionNCT01680393Bispebjerg Hospital60
已完成
不适用
Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair PositionCerebral IschemiaNCT01983618Centre hospitalier de l'Université de Montréal (CHUM)25
Unknown
不适用
Effects of Intraoperative Goal-Directed Fluid Therapy on the Incidence of Postoperative ComplicationsPostoperative ComplicationsNCT02507557First Affiliated Hospital of Chongqing Medical University400
已完成
不适用
Vasopressin to Prevent Hypotension During Beach Chair SurgeryRotator Cuff Tear ArthropathyNCT01687894Chonnam National University Hospital74