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Scoploamine in the treatment of major depressio

Phase 2
Conditions
Major Depressive episode.
Major Depressive episode
Registration Number
IRCT201201181556N31
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Presence of Major Depressive Disorder based on DSM-IV criteria; Baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 22. Exclusion criteria: Presence of Psychosis, any other diagnosis in Axis I and II; Receiving psychotropic medications; receiving any antidepressants during past one month or ECT during past two months; Presence of hypothyroidism or cardiovascular problems and pregnancy or nursing women

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity of depression. Timepoint: Baseline and day 4, 7 , 14, 28, and 42. Method of measurement: Hamiltion Depression Rating Scale 17-Item.
Secondary Outcome Measures
NameTimeMethod
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