Riluzole in the treatment of major depressio
Phase 2
- Conditions
- Major Depressive episode.Major Depressive episode
- Registration Number
- IRCT201307181556N54
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Presence of Major Depressive Disorder based on DSM-IV criteria; Baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 19. Exclusion criteria: 1. Presence of Psychosis;2.any other diagnosis in Axis I and II; 3.Receiving psychotropic medications;4.receiving any antidepressants during past one month or ECT during past two months;5. Presence of hypothyroidism;6. cardiovascular problems; 7. pregnancy or nursing women; 8.7-rising liver transaminases to three times the upper limit of normal or higher
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks 2,4 and 6. Method of measurement: Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method