Prevalence of colorectal cancer in symptomatic and asymptomatic patients undergoing total coloscopy A prospective, multi-center, case-control endoscopy study in a federal state in Germany
- Conditions
- C18Malignant neoplasm of colon
- Registration Number
- DRKS00003503
- Lead Sponsor
- niversitätsklinik Frankfurt am Main
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 6450
patients undergoing colonoscopy under outpatient conditions. Only patients undergoing first colonoscopy in life were evaluated. Symptoms included tumour-suspicious symptoms (altered bowel habits, weight loss, anaemia, anorectal bleeding, positive fecal occult blood tests (FOBT), abdominal pain, constipation or diarrhoea). Eligible patients provided written informed consent. Complete colonoscopy is mandatory.
Persons with increased risk for CRC (surveillance after resection of a CRC, surveillance after polypectomy, known inflammatory bowel disease, FAP, HNPCC) and persons with the history of colorectal surgery were excluded in both study groups. The completeness of colonoscopy was a prerequisite for inclusion in both studies as well as for reimbursement by the health insurance
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of colorectal cancer and its precursor lesions in patients undergoing total colonoscopy in comparison to screening participants.
- Secondary Outcome Measures
Name Time Method