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STunning in Acute Myocardial Infarction – Beta blockers, Angiotensin converting enzyme inhibitors and Sodium/glucose cotransporter 2 inhibitors trial (STAMI-BAS)

Phase 1
Conditions
Myocardial ischemiaMyocardial infarction
MedDRA version: 20.0Level: LLTClassification code: 10064345Term: ST segment elevation myocardial infarction Class: 10007541
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
CTIS2024-511789-35-00
Lead Sponsor
Vaestra Goetalandsregionen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
120
Inclusion Criteria

Patients with STEMI who undergo primary PCI within 6 hours of symptom onset* (*Excluding prodromal symptoms), Informed consent

Exclusion Criteria

Killip class = 3, Pre-existing non-reversible cardiac dysfunction or heart failure, Current treatment with any beta blocker, RAAS inhibitor or SGLT2 inhibitor, Absolute or relative contraindication to any one of the study drugs that confers a risk of patient safety if the patient participates in the trial and adheres to the protocol-specified recommendations, per the assessment of the treating physician, Life expectancy less than one year, Pregnancy or women of childbearing potential who is not sterilized or is not using a medically accepted form of contraception., Additional exclusion criteria for the CMRI sub-study of the trial: 7. Any absolute contraindication for CMRI

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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