STunning in Acute Myocardial Infarction - BAS
- Conditions
- Myocardial Infarct
- Registration Number
- NCT06562582
- Lead Sponsor
- Vastra Gotaland Region
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria:<br><br> 1. Patients with STEMI who undergo primary PCI within 6 hours of symptom onset<br> (Excluding prodromal symptoms)<br><br> 2. Informed consent<br><br>Exclusion Criteria:<br><br> 1. Killip class = 3<br><br> 2. Chronic kidney disease with GFR < 25 ml/min/1.73 m2<br><br> 3. Pre-existing non-reversible cardiac dysfunction or heart failure<br><br> 4. Current treatment with any beta blocker, RAAS inhibitor or SGLT2 inhibitor<br><br> 5. Absolute or relative contraindication to any one of the study drugs that confers a<br> risk of patient safety if the patient participates in the trial and adheres to the<br> protocol-specified recommendations, per the assessment of the treating physician<br><br> 6. Life expectancy less than one year<br><br> 7. Pregnancy or women of childbearing potential who is not sterilized or is not using a<br> medically accepted form of contraception
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of Global longitudinal strain (GLS, %)
- Secondary Outcome Measures
Name Time Method Measurement of Left ventricular ejection fraction (LVEF);Measurement of NT-proBNP (N-terminal pro b-type natriuretic peptide );Concentration of cardiac troponin-T;Concentration of cardiac troponin-I