Complicated Outcome Prediction After Liver Resection

Completed

• Conditions: Liver Neoplasms
• Interventions: Procedure: Liver resection for primary and secondary disease

• Registration Number: NCT03577067
• Lead Sponsor: University of Milan

Brief Summary

Although mortality after liver surgery reduced during the last three decades to less than 2%, post-operative course is still complicated in a range of 20-50% of cases.The identification of one or few factors which could detect the real risk of complicated post-operative outcome, may help anesthesiologist to decide whether admit a patient to ICU or not.The primary aim of this study was to evaluate whether RRI, alone or along with other items, can predict post-operative complication after hepatic resection.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-02
• Primary Completion: 2017-03
• Study Completion: 2017-03
• Study First Submitted: 2018-05-28
• Status Verified: 2018-07
• Study First Submitted QC: 2018-07-02
• Last Update Submitted: 2018-07-02
• Study First Posted: 2018-07-05
• Last Update Posted: 2018-07-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 183

Inclusion Criteria

Patients resectable and affected by primary and secondary liver disease

Exclusion Criteria

Subjects affected by kidney disease and/or cirrhosis and pregnant patients were excluded from the trial. Patients who should have needed nephrectomy during the operation would be also excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients submitted to liver resection	Liver resection for primary and secondary disease	Patients underwent liver resection for primary and secondary disease

Primary Outcome Measures

Name	Time	Method
renal resistive index (RRI)	up to 7 days after surgery	the association between RRI and occurrence of hepatic complications during the first postoperative week.