Triclosan-coated sutures versus uncoated sutures for prevention of surgical site infection after abdominal wall closure in open/laparoscopic colorectal surgery
Not Applicable
- Conditions
- Surgical site infection
- Registration Number
- JPRN-UMIN000042605
- Lead Sponsor
- Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group
- Brief Summary
The recorded SSI rates were 4.2% in the triclosan-coated group and 6.74% in the uncoated suture group (p = 0.028). There were no serious adverse events in the groups. The final logistic regression model showed that several variables affected the occurrence of SSI. Our meta-analysis included six phase-III trials, and our study evaluated 4,797 patients. The results show a significant superiority of triclosan-coated sutures over uncoated suture material.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 2207
Inclusion Criteria
Not provided
Exclusion Criteria
1) There is no history of surgical wounds on the planned surgical site. 2) Do not perform surgery on other organs in different locations at the same time. 3) No history of radiation therapy or chemotherapy. 4) No contamination or infection surgery.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method