ipid-lowering effects of ACTH
- Conditions
- Healthy male volunteers
- Registration Number
- EUCTR2005-005438-11-IS
- Lead Sponsor
- niv. of Iceland, Dept. Pharmacol.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Healthy, male, age 18-60 years.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
History of endocrine-, renal-, malignant or inflammatory disease. Treatment with a drug that affects blood-lipids. Allergy for Synacthen Depot og any other drug containing ACTH. Cooperation problems.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To establish the blood-lipid lowering effetcts of ACTH. <br>To find the most appropriate dosing interval that gives a steady lipid-lovering effect.;Secondary Objective: Recording of adverse reactions.;Primary end point(s): Serum concentration of LDL-cholesterol and apolipoprotein-B.
- Secondary Outcome Measures
Name Time Method