Comparison of Choosing Free ALT or Free PMT for Reconstruction With Head and Neck Cancer

Completed

• Conditions: Reconstructive Surgery; Head and Neck Cancer
• Interventions: Other: ALT flap reconstruction; Other: AMT flap reconstruction

• Registration Number: NCT04002713
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

This study was designed to compare the outcome of the anteromedial thigh (AMT) and anterolateral thigh (ALT) flaps in head and neck cancer reconstruction.

Detailed Description

To compare the results of the AMT and ALT flaps, this study aimed to compare their outcomes in head and neck cancer reconstruction under the condition of attenuating baseline patient and operative characteristics with the selection of propensity score-matched patient cohorts.

Study Timeline

• Study Start: 2019-03-20
• Primary Completion: 2019-05-02
• Status Verified: 2019-06
• Study Completion: 2019-06-03
• Study First Submitted: 2019-06-27
• Study First Submitted QC: 2019-06-27
• Last Update Submitted: 2019-06-27
• Study First Posted: 2019-07-01
• Last Update Posted: 2019-07-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1590

Inclusion Criteria

• Patients who underwent ALT or AMT free flap reconstruction after head and neck cancer surgery between March 1, 2008 and February 28, 2017.

Exclusion Criteria

• Patients whose data were missing will be excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ALT&AMT free flap reconstruction	ALT flap reconstruction	Patients who underwent ALT or AMT free flap reconstruction after head and neck cancer surgery between March 1, 2008 and February 28, 2017
ALT&AMT free flap reconstruction	AMT flap reconstruction	Patients who underwent ALT or AMT free flap reconstruction after head and neck cancer surgery between March 1, 2008 and February 28, 2017

Primary Outcome Measures

Name	Time	Method
survival or failure	up to 6 months	The primary free flap outcome was determined as its survival or failure.

Secondary Outcome Measures

Name	Time	Method
Complications	up to 6 months	The second outcome was the associated complications (fistula, hematoma, partial necrosis, and wound infection).

Trial Locations

Locations (1)

Kaohsiung Chang Gung Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan