A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Crohn's Disease Who Failed Prior Biologic Treatment
- Conditions
- Crohn's Disease
- Interventions
- Registration Number
- NCT03104413
- Lead Sponsor
- AbbVie
- Brief Summary
The objective of Study M15-991 is to evaluate the efficacy and safety of risankizumab versus placebo during induction therapy in participants with moderately to severely active CD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 618
- Male or female aged >=18 to <= 80 years, or minimum age of adult consent according to local regulations, at the Baseline Visit. Where locally permissible, participants 16 to < 18 years of age who meet the definition of Tanner stage 5 for development at the Baseline Visit.
- Confirmed diagnosis of CD for at least 3 months prior to Baseline.
- Crohn's disease activity index (CDAI) score 220 - 450 at Baseline.
- Confirmed diagnosis of moderate to severe CD as assessed by stool frequency (SF), abdominal pain (AP) score, and Simple Endoscopic Score for Crohn's Disease (SES-CD).
- Demonstrated intolerance or inadequate response to biologic therapy for CD.
- If female, participant must meet the contraception recommendations.
- Participant with a current diagnosis of ulcerative colitis or indeterminate colitis.
- Participants with unstable doses of concomitant Crohn's disease therapy.
- Receipt of Crohn's disease approved biologic agents (infliximab, adalimumab, certolizumab, vedolizumab, natalizumab within 8 weeks prior to Baseline or ustekinumab within 12 weeks prior to Baseline), or any investigational biologic or other agent or procedure within minimally 35 days or 5 half-lives prior to Baseline, whichever is longer.
- Prior exposure to p19 inhibitors (e.g., risankizumab).
- Complications of Crohn's disease.
- Having an ostomy or ileoanal pouch.
- Known active Coronavirus Disease 2019 (COVID-19) infection.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Risankizumab Dose 2 (Induction Period 2) risankizumab SC Participants with inadequate response at Week 12 in Period 1 randomized to receive risankizumab dose 2 administered by subcutaneous (SC) injection in Period 2. Risankizumab Dose 3 (Induction period 2) risankizumab SC Participants with inadequate response at Week 12 in Period 1 randomized to receive risankizumab dose 3 administered by subcutaneous (SC) injection in Period 2. Risankizumab Dose 1 (Induction Period 1) risankizumab IV Participants randomized to receive risankizumab dose 1 in Induction Period 1. Risankizumab Dose 2 (Induction Period 1) risankizumab IV Participants randomized to receive risankizumab dose 2 in Induction Period 1. Placebo (Induction Period 1) placebo for risankizumab IV Participants randomized to receive placebo for risankizumab in Induction Period 1. Risankizumab Dose 1 (Induction Period 2) risankizumab IV Participants who received placebo in Period 1 and participants with inadequate response at Week 12 in Period 1 randomized to receive risankizumab dose 1 administered by intravenous (IV) infusion in Period 2.
- Primary Outcome Measures
Name Time Method US Specific: Percentage of Participants With Endoscopic Response Week 12 The SES-CD assesses endoscopic disease severity by evidence of active intestinal mucosal inflammation. Endoscopic response is defined as a decrease in SES-CD \> 50% from Baseline (or for participants with isolated ileal disease and a Baseline SES-CD of 4, at least a 2-point reduction from Baseline).
US Specific: Percentage of Participants With Crohn's Disease Activity Index (CDAI) Clinical Remission Week 12 The CDAI consists of 8 components; 7 are based on participant diary entries, participant interviews, physical examinations, measurement of body weight and height and 1 is based on laboratory analysis. CDAI clinical remission of Crohn's disease is defined as CDAI \< 150.
Global Outside of US: Percentage of Participants With Clinical Remission Week 12 Clinical remission is defined as using the average daily Stool Frequency (SF) ≤ 2.8 and not worse than Baseline AND average daily Abdominal Pain (AP) score ≤ 1 and not worse than Baseline.
Global Outside of US: Percentage of Participants With Endoscopic Response Week 12 The SES-CD assesses endoscopic disease severity by evidence of active intestinal mucosal inflammation. Endoscopic response is defined as a decrease in SES-CD \> 50% from Baseline (or for participants with isolated ileal disease and a Baseline SES-CD of 4, at least a 2-point reduction from Baseline).
- Secondary Outcome Measures
Name Time Method US Specific: Percentage of Participants With Ulcer-Free Endoscopy Week 12 Ulcer-free endoscopy: SES-CD ulcerated surface subscore of 0 in subjects with SES-CD ulcerated surface subscore ≥ 1 at Baseline
US Specific: Percentage of Participants With Resolution of Extra-Intestinal Manifestations (EIMs), in Participants With EIMs at Baseline Baseline Week 12 Manifestations of Crohn's disease in areas of the body other than the digestive tract, including eyes, skin, joints, mouth, and liver.
US Specific: Percentage of Participants With CD-Related Hospitalization Up to Week 12 Participants with at least one admission to the hospital due to Crohn's Disease.
Global Outside of US: Change From Baseline of Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Week 12 The FACIT-Fatigue scale is a 13-item tool that measures an individual's level of fatigue during their usual daily activities over the past 7 days. Each of the fatigue and impact of fatigue items are measured on a four point Likert scale. The FACIT Fatigue Scale is the sum of the individual 13 scores and ranges from 0 to 52 where higher scores indicate better the quality of life. A positive change from baseline indicates improvement.
US Specific: Percentage of Participants With Clinical Remission Week 12 Clinical remission is defined as using the average daily Stool Frequency (SF) ≤ 2.8 and not worse than Baseline AND average daily Abdominal Pain (AP) score ≤ 1 and not worse than Baseline.
US Specific: Change From Baseline of Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Week 12 The FACIT-Fatigue scale is a 13-item tool that measures an individual's level of fatigue during their usual daily activities over the past 7 days. Each of the fatigue and impact of fatigue items are measured on a four point Likert scale. The FACIT Fatigue Scale is the sum of the individual 13 scores and ranges from 0 to 52 where higher scores indicate better the quality of life. A positive change from baseline indicates improvement.
US Specific: Percentage of Participants With Crohn's Disease Activity Index (CDAI) Clinical Remission Week 4 Crohn's Disease Activity Index (CDAI) is used to assess the symptoms of participants with Crohn's Disease. Higher CDAI scores indicate more severe disease. CDAI clinical remission of Crohn's disease is defined as CDAI \< 150.
US Specific: Percentage of Participants With CDAI Clinical Response and Endoscopic Response Week 12 Crohn's Disease Activity Index (CDAI) is used to assess the symptoms of participants with Crohn's Disease. Higher CDAI scores indicate more severe disease. CDAI clinical response is defined as reduction of CDAI ≥ 100 points from baseline.
Endoscopic response was a decrease in Simplified Endoscopic Score for Crohn's Disease (SES-CD) \> 50% from Baseline (or for subjects with isolated ileal disease and a Baseline SES-CD of 4, at least a 2 point reduction from Baseline).US Specific: Percentage of Participants With Crohn's Disease Activity Index (CDAI) Clinical Response Week 12 Crohn's Disease Activity Index (CDAI) is used to assess the symptoms of participants with Crohn's Disease. Higher CDAI scores indicate more severe disease. CDAI clinical response is defined as reduction of CDAI ≥ 100 points from baseline.
US Specific: Percentage of Participants With Abdominal Pain (AP) Remission Week 12 The Abdominal Pain rating is an assessment that is graded from 0 to 3: 0= None, 1= Mild, 2= Moderate and 3= Severe. AP remission is defined as average daily AP score \<= 1 and not worse than baseline.
US Specific: Percentage of Participants With Enhanced Clinical Response Week 12 Enhanced clinical response: ≥ 60% decrease in average daily SF and/or ≥ 35% decrease in average daily AP score and both not worse than Baseline, and/or clinical remission
US Specific: Percentage of Participants With Stool Frequency (SF) Remission Week 12 Stool Frequency (SF) remission is defined as an average daily SF \<= 2.8 and not worse than baseline.
US Specific: Percentage of Participants With Endoscopic Remission Week 12 Endoscopic remission: SES-CD ≤ 4 and at least a 2 point reduction versus baseline and no subscore greater than 1 in any individual variable
US Specific: Percentage of Participants Without Draining Fistulas in Participants With Draining Fistulas at Baseline Week 12 Participants without draining fistulas at Week 12 in participants who had draining fistulas at baseline.
Global Outside of US: Percentage of Participants With Crohn's Disease Activity Index (CDAI) Clinical Remission Week 12 The CDAI consists of 8 components; 6 are based on participant diary entries, participant interviews, and physical examinations, and 2 are based on laboratory analysis, and measurement of body weight and height. CDAI clinical remission of Crohn's disease is defined as CDAI \< 150.
Global Outside of US: Percentage of Participants With Crohn's Disease Activity Index (CDAI) Clinical Response Week 12 Crohn's Disease Activity Index (CDAI) is used to assess the symptoms of participants with Crohn's Disease. Higher CDAI scores indicate more severe disease. CDAI clinical response is defined as reduction of CDAI ≥ 100 points from baseline.
Global Outside of US: Percentage of Participants With Clinical Remission Week 4 Clinical remission is defined as using the average daily Stool Frequency (SF) ≤ 2.8 and not worse than Baseline AND average daily Abdominal Pain (AP) score ≤ 1 and not worse than Baseline.
Global Outside of US: Change From Baseline in Inflammatory Bowel Disease Questionnaire (IBDQ) Total Score Week 12 The IBDQ is a 32-item (ranges 1 - 7) self-report questionnaire for patients with IBD to evaluate the patient reported outcomes across 4 dimensions: bowel symptoms (loose stools, abdominal pain), systemic symptoms (fatigue, altered sleep pattern), social function (work attendance, need to cancel social events), and emotional function (anger, depression, irritability). The IBDQ total Score ranges from 32 to 224 with a higher score indicating better outcome.
Global Outside of US: Percentage of Participants With Enhanced Clinical Response and Endoscopic Response Week 12 Enhanced clinical response was defined as ≥ 60% decrease in average daily Stool Frequency and/or ≥ 35% decrease in average daily Abdominal Pain score and both not worse than baseline, and/or clinical remission. Endoscopic Response was defined as a decrease in Simplified Endoscopic Score for Crohn's Disease (SES-CD) \> 50% from Baseline (or for subjects with isolated ileal disease and a Baseline SES-CD of 4, at least a 2 point reduction from Baseline).
Global Outside of US:: Percentage of Participants With Endoscopic Remission Week 12 Endoscopic remission: SES-CD ≤ 4 and at least a 2 point reduction versus baseline and no subscore greater than 1 in any individual variable
Global Outside of US: Percentage of Participants With Enhanced Clinical Response Week 12 Enhanced clinical response: ≥ 60% decrease in average daily SF and/or ≥ 35% decrease in average daily AP score and both not worse than Baseline, and/or clinical remission
Global Outside of US: Percentage of Participants With Ulcer-Free Endoscopy Week 12 Ulcer-free endoscopy: SES-CD ulcerated surface subscore of 0 in subjects with SES-CD ulcerated surface subscore ≥ 1 at Baseline
Global Outside of US: Percentage of Participants With Resolution of Extra-Intestinal Manifestations (EIMs), in Participants With EIMs at Baseline Baseline Week 12 Manifestations of Crohn's disease in areas of the body other than the digestive tract, including eyes, skin, joints, mouth, and liver.
Global Outside of US: Percentage of Participants With CD-Related Hospitalization Week 12 Participants with at least one admission to the hospital due to Crohn's Disease.
Global Outside of US: Percentage of Participants Without Draining Fistulas in Participants With Draining Fistulas at Baseline Week 12 Participants without draining fistulas at Week 12 in participants who had draining fistulas at baseline.
Global Outside of US: Change From Baseline in Work Productivity and Impairment Questionnaire - Crohn's Disease (WPAI-CD) Overall Work Impairment Week 12 WPAI: CD is a questionnaire used to evaluate lost productivity due to CD ; scores are presented as percentages (multiplying the scores by 100), with 0% representing no impact on productivity and 100% representing complete impact on productivity. Total work productivity impairment takes into account both hours missed due to CD symptoms and the patient's assessment of the degree to which CD affected their productivity while working (overall work impairment \[OWI\]). WPAI outcomes are expressed as impairment percentages, with higher numbers indicating greater impairment and less productivity.
Global Outside of US: Change From Baseline in Short Form-36 (SF-36) Physical Component Summary (PCS) Score Week 12 The Short Form-36 Health Survey determined participants' overall quality of life by assessing 1) limitations in physical functioning due to health problems; 2) limitations in usual role because of physical health problems; 3) bodily pain; 4) general health perceptions; 5) vitality; 6) limitations in social functioning because of physical or emotional problems; 7) limitations in usual role due to emotional problems; and 8) general mental health. Items 1-4 comprise the physical component of the SF-36. Scores on each item were summed and averaged (range = 0-100); a positive change from Baseline indicates improvement.
Trial Locations
- Locations (403)
TLC Clinical Research Inc /ID# 212501
🇺🇸Los Angeles, California, United States
Children's Hospital of Pittsburgh of UPMC /ID# 212543
🇺🇸Pittsburgh, Pennsylvania, United States
Duplicate_Atria Clinical Research /ID# 164504
🇺🇸Little Rock, Arkansas, United States
SIH Research Mumtaz, Inc /ID# 163081
🇺🇸Kissimmee, Florida, United States
HonorHealth Research Institute - Shea /ID# 165825
🇺🇸Scottsdale, Arizona, United States
Clinical Research of West Florida, Inc /ID# 208127
🇺🇸Clearwater, Florida, United States
Newport Huntington Medica /ID# 213034
🇺🇸Huntington Beach, California, United States
Cfagi Llc /Id# 202482
🇺🇸Maitland, Florida, United States
Gastroenterology Group Naples /ID# 165192
🇺🇸Naples, Florida, United States
IMIC Inc. Medical Research /ID# 154944
🇺🇸Palmetto Bay, Florida, United States
Duplicate_Long Island Clinical Research /ID# 154843
🇺🇸Great Neck, New York, United States
Tyler Research Institute, LLC /ID# 166795
🇺🇸Tyler, Texas, United States
Washington Gastroenterology Associates /ID# 162101
🇺🇸Bellevue, Washington, United States
UCL Saint-Luc /ID# 157384
🇧🇪Woluwe-Saint-Lambert, Bruxelles-Capitale, Belgium
Mater Misericordiae Limited /ID# 167216
🇦🇺South Brisbane, Queensland, Australia
Griffith University /ID# 212631
🇦🇺Southport, Queensland, Australia
Weill Cornell Medicine /ID# 165856
🇺🇸New York, New York, United States
Baylor Scott & White Medical Center- Temple /ID# 204129
🇺🇸Temple, Texas, United States
UMHAT Dr Georgi Stranski EAD /ID# 203975
🇧🇬Pleven, Bulgaria
Adult Gastroenterology Associates - Gen 1 Research /ID# 208857
🇺🇸Tulsa, Oklahoma, United States
ZNA - Jan Palfijn /ID# 212822
🇧🇪Merksem, Belgium
Cemic /Id# 168082
🇦🇷Ciudad Autonoma de Buenos Aire, Ciuadad Autonoma De Buenos Aires, Argentina
Hospital Privado Univesitario /ID# 168080
🇦🇷Cordoba, Argentina
UZ Gent /ID# 157383
🇧🇪Gent, Oost-Vlaanderen, Belgium
Second Multiprofile Hospital f /ID# 165699
🇧🇬Sofia, Bulgaria
WVU Medicine /ID# 167942
🇺🇸Morgantown, West Virginia, United States
Velocity Clinical Research - Salt Lake City /ID# 161775
🇺🇸West Jordan, Utah, United States
Vitebsk Regional Advanced Clin /ID# 204807
🇧🇾Витебск, Belarus
Hospital Provincial del Centenario /ID# 170904
🇦🇷Rosario, Santa Fe, Argentina
Hospital Britanico de Buenos Aires /ID# 168081
🇦🇷Ciudad Autonoma de Buenos Aire, Ciuadad Autonoma De Buenos Aires, Argentina
Advanced Research Institute /ID# 154922
🇺🇸Ogden, Utah, United States
Hospital Guillermo Grant Benavente de Concepción /ID# 210758
🇨🇱Concepción, Chile
Gastro Health & Nutrition - Victoria /ID# 164284
🇺🇸Victoria, Texas, United States
University Multiprofile Hospit /ID# 165697
🇧🇬Plovdiv, Bulgaria
UMHAT Sveti Ivan Rilski /ID# 204713
🇧🇬Sofia, Bulgaria
Duplicate_Medical University of Vienna /ID# 158135
🇦🇹Vienna, Wien, Austria
Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 210857
🇨🇳Wuhan, Hubei, China
IWK Health Center /ID# 165909
🇨🇦Halifax, Nova Scotia, Canada
AZ Sint-Maarten /ID# 212280
🇧🇪Mechelen, Antwerpen, Belgium
Allen Whey Khye Lim Professional Corporation /ID# 169766
🇨🇦Edmonton, Alberta, Canada
Hospital Univ San Ignacio /ID# 158737
🇨🇴Bogota, Cundinamarca, Colombia
Klinicki bolnicki centar Sestre milosrdnice /ID# 157720
🇭🇷Zagreb, Grad Zagreb, Croatia
Klinicki bolnicki centar Zagreb /ID# 157703
🇭🇷Zagreb, Grad Zagreb, Croatia
West China Hospital, Sichuan University /ID# 210888
🇨🇳Chengdu, China
London Health Sciences Center /ID# 157162
🇨🇦London, Ontario, Canada
Covenant Health /ID# 161636
🇨🇦Edmonton, Alberta, Canada
University Multiprofile Hospit /ID# 167576
🇧🇬Varna, Bulgaria
UHC Osijek /ID# 157704
🇭🇷Osijek, Osjecko-baranjska Zupanija, Croatia
Scott Shulman Medicine Professional Corporation /ID# 165910
🇨🇦North Bay, Ontario, Canada
Thomayerova nemocnice /ID# 162942
🇨🇿Praha, Czechia
Hospital Las Higueras /ID# 167091
🇨🇱Talcahuano, Chile
ResTrial s.r.o. /ID# 211074
🇨🇿Praha, Czechia
Nemocnice Milosrdnych sester sv. Karla Boromejskeho v Praze /ID# 211304
🇨🇿Praha, Czechia
Sygehusenheden Nyborg - OUH /ID# 161591
🇩🇰Nyborg, Syddanmark, Denmark
CHU Montpellier - Hôpital Saint Eloi /ID# 215146
🇫🇷Montpellier Cedex 5, Herault, France
Universitaetsklinikum Frankfurt /ID# 212977
🇩🇪Frankfurt am Main, Hessen, Germany
Universitaetsklinikum Koeln /ID# 164987
🇩🇪Köln, Nordrhein-Westfalen, Germany
Universitaetsklinikum Ulm /ID# 164988
🇩🇪Ulm, Baden-Wuerttemberg, Germany
Nemocnice Pardubickeho kraje, a.s. /ID# 163219
🇨🇿Pardubice, Czechia
Clinical Research Center, Faculty of Medicine, Cairo university /ID# 157176
🇪🇬Cairo, Egypt
Hepato-Gastroenterologie HK, s.r.o. /ID# 163218
🇨🇿Hradec Kralove, Czechia
Hospital Pontchaillou /ID# 213207
🇫🇷Rennes, France
East Tallinn Central Hospital /ID# 157072
🇪🇪Tallinn, Harjumaa, Estonia
Duplicate_Institut klinicke a experimentalni mediciny (IKEM) /ID# 165479
🇨🇿Prague 4, Praha 4, Czechia
Zadar General Hospital /ID# 157706
🇭🇷Zadar, Croatia
Universitaetsklinikum Tuebingen /ID# 159341
🇩🇪Tübingen, Baden-Wuerttemberg, Germany
CHU de SAINT ETIENNE - Hopital Nord /ID# 162550
🇫🇷St. Priest En Jarez, Loire, France
Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 164423
🇪🇬Alexandria, Egypt
EUGASTRO GmbH /ID# 212077
🇩🇪Leipzig, Germany
Shaare Zedek Medical Center /ID# 163539
🇮🇱Jerusalem, Israel
Stadtisches Klinikum Braunschweig /ID# 163673
🇩🇪Braunschweig, Germany
Agaplesion Markus Krankenhaus /ID# 159334
🇩🇪Frankfurt am Main, Germany
Universitaetsklinikum Magdeburg /ID# 211840
🇩🇪Magdeburg, Germany
DRK Kliniken Berlin Westend /ID# 166149
🇩🇪Berlin, Germany
Duplicate_Azienda Ospedaliero-Universitaria Policlinico di Modena /ID# 212018
🇮🇹Modena, Emilia-Romagna, Italy
Gastroenterologische Gemeinschaftspraxis Minden /ID# 162024
🇩🇪Minden, Germany
Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 212218
🇩🇪Berlin, Germany
General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 157418
🇬🇷Athens, Greece
University General Hospital of Ioannina /ID# 157415
🇬🇷Ioannina, Greece
Theageneio Anticancer Hospital /ID# 163922
🇬🇷Thessaloniki, Greece
Praxis fuer Gastroenterologie /ID# 166148
🇩🇪Heidelberg, Baden-Wuerttemberg, Germany
Duplicate_Universitaetsklinikum Freiburg /ID# 162025
🇩🇪Freiburg, Germany
Universitaetsklinikum Erlangen /ID# 159332
🇩🇪Erlangen, Bayern, Germany
CHU Grenoble - Hopital Michallon /ID# 211980
🇫🇷La Tronche, France
Praxiszentrum fuer Gastroenterologie /ID# 211965
🇩🇪Grevenbroich, Nordrhein-Westfalen, Germany
MVZ fuer Gastroenterlogie am Bayerischen Platz /ID# 159339
🇩🇪Berlin, Germany
Tzaneio general hospital of Piraeus /ID# 206441
🇬🇷Piraeus, Attiki, Greece
General Hospital of Nikaia-Piraeus "Agios Panteleimon"- general hospital dytikis /ID# 157419
🇬🇷Pireaus, Greece
A.O. Per L'Emergenza Cannizzaro /ID# 161303
🇮🇹Catania, Italy
Klinikum Lueneburg /ID# 163671
🇩🇪Lueneburg, Germany
Duplicate_Dong-A University Hospital /ID# 163370
🇰🇷Busan, Korea, Republic of
Planetmed Sp. z o.o. /ID# 205159
🇵🇱Wroclaw, Dolnoslaskie, Poland
Pusan National University Hospital /ID# 163376
🇰🇷Busan, Korea, Republic of
Duplicate_Rambam Medical Center /ID# 171056
🇮🇱Haifa, Israel
Duplicate_Wellington Hospital (Capital and Coast District Health Board) /ID# 167213
🇳🇿Wellington, New Zealand
Presidio Columbus-Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Un /ID# 155656
🇮🇹Rome, Roma, Italy
Uniwersytecki Szpital Kliniczny nr 1 im. Norberta Barlickiego w Lodzi /ID# 212290
🇵🇱Lodz, Lodzkie, Poland
Centrum Zdrowia MDM /ID# 163602
🇵🇱Warszawa, Mazowieckie, Poland
Centralny Szpital Kliniczny MSWiA w Warszawie /ID# 163604
🇵🇱Warszawa, Mazowieckie, Poland
Severance Hospital /ID# 163374
🇰🇷Seoul, Seoul Teugbyeolsi, Korea, Republic of
Christchurch Hospital /ID# 167212
🇳🇿Christchurch, Canterbury, New Zealand
Centrum Medyczne Medyk /ID# 212888
🇵🇱Rzeszów, Podkarpackie, Poland
Shaare Zedek Medical Center /ID# 171055
🇮🇱Jerusalem, Israel
Yeungnam University Medical Center /ID# 163366
🇰🇷Daegu, Korea, Republic of
Kangbuk Samsung Hospital /ID# 163354
🇰🇷Seoul, Seoul Teugbyeolsi, Korea, Republic of
Unidad de Atencion Medica e Investigacion en Salud /ID# 170765
🇲🇽Merida, Yucatan, Mexico
Health Pharma Professional Research S.A de C.V /ID# 170763
🇲🇽Del. Benito Juárez, Mexico
Centrum Medyczne LukaMed Joanna Luka-Wendrowska /ID# 212079
🇵🇱Chojnice, Pomorskie, Poland
Wojewodzki Szpital Specjalistyczny /ID# 212400
🇵🇱Olsztyn, Warminsko-mazurskie, Poland
Duplicate_Niepubliczny Zakład Opieki Zdrowotnej VIVAMED Jadwiga Miecz /ID# 202434
🇵🇱Warsaw, Poland
Fondazione PTV Policlinico Tor Vergata /ID# 158023
🇮🇹Rome, Roma, Italy
ASST Fatebenefratelli Sacco-Ospedale Sacco /ID# 155655
🇮🇹Milano, Italy
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 155657
🇮🇹Milan, Italy
Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 160691
🇵🇹Guimaraes, Braga, Portugal
1 Wojskowy Szpital Kliniczny Z Poliklinika /Id# 209984
🇵🇱Lublin, Lubelskie, Poland
Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 213578
🇵🇱Warszawa, Mazowieckie, Poland
Middlemore Clinical Trials /ID# 167214
🇳🇿Auckland, New Zealand
Tver Regional Clinical Hospital /ID# 206586
🇷🇺Tver, Tverskaya Oblast, Russian Federation
Centro Hospitalar Universitario de Sao Joao, EPE /ID# 160742
🇵🇹Porto, Portugal
Duplicate_Centrul Medical Tuculanu SRL /ID# 170892
🇷🇴Timisoara, Romania
National Taiwan University Hospital /ID# 162189
🇨🇳Taipei City, Taiwan
Zagazig University Hospitals /ID# 164018
🇪🇬Al Sharqia, Egypt
Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 157876
🇪🇬Alexandria, Egypt
National Hepatology and Tropical Medicine Research Institute /ID# 157875
🇪🇬Cairo, Egypt
St Vincent's University Hospital /ID# 157569
🇮🇪Elm Park, Dublin, Ireland
Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 210527
🇩🇪Saarbrücken, Saarland, Germany
Universitätsspital Basel /ID# 166321
🇨🇭Basel, Basel-Stadt, Switzerland
IRCCS Ospedale Sacro Cuore Don Calabria /ID# 161302
🇮🇹Negrar, Verona, Italy
CHRU Nancy - Hôpitaux de Brabois /ID# 162549
🇫🇷Vandœuvre-lès-Nancy, Meurthe-et-Moselle, France
Beaumont Hospital /ID# 157572
🇮🇪Beaumont, Dublin, Ireland
The Sixth Affiliated Hosp Sun /ID# 210783
🇨🇳Guangzhou, Guangdong, China
Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 211040
🇨🇳Wuhan, Hubei, China
Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 210706
🇨🇳Shanghai, Shanghai, China
The First Affiliated Hospital of Nanchang University /ID# 211035
🇨🇳Nanchang, Jiangxi, China
Shanghai East Hospital /ID# 212671
🇨🇳Pudong New District, China
Duplicate_Tianjin Med Univ General Hosp /ID# 210925
🇨🇳Tianjin, China
Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 155535
🇩🇰Hvidovre, Hovedstaden, Denmark
Aarhus University Hospital /ID# 155534
🇩🇰Aarhus N, Midtjylland, Denmark
Krankenhaus der Barmherzigen Brueder Wien /ID# 211418
🇦🇹Vienna, Wien, Austria
Instituto de Coloproctologia /ID# 158740
🇨🇴Medellin, Antioquia, Colombia
Duplicate_Ospedale Policlinico San Martino/ Università Degli Studi Di Genova /ID# 162434
🇮🇹Genoa, Liguria, Italy
Duplicate_Policlinico Universitario Campus Bio-Medico /ID# 162433
🇮🇹Rome, Lazio, Italy
Complejo Asistencial Dr. Sotero del Rio /ID# 169383
🇨🇱Santiago, Region Metropolitana De Santiago, Chile
University Clinical Centre of the Republic of Srpska /ID# 157710
🇧🇦Banja Luka, Republika Srpska, Bosnia and Herzegovina
Chu de Nice-Hopital L'Archet Ii /Id# 162545
🇫🇷Nice, Alpes-Maritimes, France
GIRI Gastrointestinal Research Institute /ID# 157097
🇨🇦Vancouver, British Columbia, Canada
Percuro Clinical Research, Ltd /ID# 161635
🇨🇦Victoria, British Columbia, Canada
Hospital Pablo Tobon Uribe /ID# 158732
🇨🇴Medellín, Antioquia, Colombia
West Tallinn Central Hospital /ID# 157073
🇪🇪Tallinn, Estonia
Duplicate_AOU Ospendali Riuniti di Ancona /ID# 162431
🇮🇹Torrette, Ancona, Italy
Queen Elizabeth Hospital /ID# 160659
🇲🇾Division Pantai Barat Utara, Sabah, Malaysia
Tvm Med Serv Srl /Id# 170891
🇷🇴Cluj, Romania
University Clinical Center Serbia /ID# 156957
🇷🇸Belgrade, Beograd, Serbia
Universitätsspital Zürich /ID# 163528
🇨🇭Zürich, Zuerich, Switzerland
CHU Amiens-Picardie Site Sud /ID# 165056
🇫🇷Amiens CEDEX 1, Somme, France
Azienda Ospedaliera San Camillo Forlanini /ID# 155660
🇮🇹Rome, Lazio, Italy
Duplicate_Universita di Catanzaro Magna Graecia /ID# 212017
🇮🇹Catanzaro, Calabria, Italy
Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 166910
🇮🇹Rome, Lazio, Italy
Pauls Stradins Clinical University Hospital /ID# 159616
🇱🇻Riga, Latvia
Riga East Clinical University Hospital /ID# 159615
🇱🇻Riga, Latvia
Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 162584
🇱🇹Kaunas, Lithuania
Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 201362
🇲🇾Kuala Lumpur, Selangor, Malaysia
Vinius University Hospital Santaros Klinikos /ID# 162524
🇱🇹Vilnius, Lithuania
Universiti Sains Malaysia /ID# 160661
🇲🇾Kelantan, Malaysia
National University Hospital /ID# 160662
🇸🇬Singapore, Singapore
Singapore General Hospital /ID# 160663
🇸🇬Singapore, Singapore
Centro Hospitalar Universitário do Algarve, EPE - Hospital de Portimão /ID# 167754
🇵🇹Portimão, Faro, Portugal
Centro Hospitalar de Entre Douro e Vouga /ID# 160676
🇵🇹Santa Maria Da Feira, Porto, Portugal
Centro Hospitalar de Lisboa Ocidental, EPE - Hospital Egas Moniz /ID# 167753
🇵🇹Lisboa, Portugal
KL Ling Gastroenterology and Liver Clinic /ID# 205736
🇸🇬Singapore, Singapore
Centro Hospitalar Universitário do Algarve, EPE - Hospital Faro /ID# 160732
🇵🇹Faro, Portugal
Duplicate_Institutul Clinic Fundeni /ID# 170888
🇷🇴Bucharest, Romania
Cabinet Particular Policlinic Algomed /ID# 170889
🇷🇴Timișoara, Romania
University Clinical Center Kragujevac /ID# 156961
🇷🇸Kragujevac, Sumadijski Okrug, Serbia
Duplicate_Clin Hosp Ctr Bezanijska Kosa /ID# 156959
🇷🇸Belgrade, Beograd, Serbia
Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 156453
🇸🇰Banska Bystrica, Slovakia
Taichung Veterans General Hosp /ID# 160134
🇨🇳Taichung, Taiwan
China Medical University Hosp /ID# 160130
🇨🇳Taichung City, Taiwan
ASST Rhodense/Presidio Ospedaliero di Rho /ID# 211453
🇮🇹Rho, Milano, Italy
Duplicate_Azienda Ospedaliera Univ. Meyer /ID# 168049
🇮🇹Florence, Toscana, Italy
A.O.U. di Bologna Policlinico S.Orsola-Malpighi /ID# 155659
🇮🇹Bologna, Italy
Duplicate_Fondazione IRCCS Policlinico S. Matteo /ID# 212030
🇮🇹Pavia, Italy
CISSS de la Monteregie /ID# 161634
🇨🇦Greenfield Park, Quebec, Canada
CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 159058
🇨🇦Montreal, Quebec, Canada
CHUM - Centre hospitalier de l'Universite de Montréal /ID# 167070
🇨🇦Montreal, Quebec, Canada
Montreal General Hospital - McGill University Health Center /ID# 157086
🇨🇦Montreal, Quebec, Canada
University of Calgary - Heritage Medical Research Clinic /ID# 157156
🇨🇦Calgary, Alberta, Canada
The Catholic University of Korea, ST. Vincent's Hospital /ID# 163365
🇰🇷Suwon, Gyeonggido, Korea, Republic of
Inje University Haeundae Hospital /ID# 202516
🇰🇷Busan, Korea, Republic of
Samsung Medical Center /ID# 163426
🇰🇷Seoul, Korea, Republic of
The Catholic University of Korea, Daejeon St.Mary's Hospital /ID# 213553
🇰🇷Daejeon, Korea, Republic of
Northwest Gastroenterology Clinic /ID# 158255
🇺🇸Portland, Oregon, United States
Vanderbilt University Medical Center /ID# 157110
🇺🇸Nashville, Tennessee, United States
Vilo Research Group Inc /ID# 207654
🇺🇸Houston, Texas, United States
CliniCore International, LLC /ID# 158191
🇺🇸Houston, Texas, United States
Baylor College of Medicine - Baylor Medical Center /ID# 158194
🇺🇸Houston, Texas, United States
Precision Research Institute, LLC /ID# 201072
🇺🇸Houston, Texas, United States
Mayo Clinic - Rochester /ID# 163084
🇺🇸Rochester, Minnesota, United States
Universitaetsklinikum Muenster /ID# 159333
🇩🇪Muenster, Nordrhein-Westfalen, Germany
Universitaetsklinikum Regensburg /ID# 163812
🇩🇪Regensburg, Germany
Gastroenterologische Spezialpraxis am Wittenbergplatz /ID# 211976
🇩🇪Berlin, Germany
University of Nebraska Medical Center /ID# 210056
🇺🇸Omaha, Nebraska, United States
Revival Research Institute, Inc /ID# 210986
🇺🇸Las Vegas, Nevada, United States
Hightower Clinical /ID# 211992
🇺🇸Oklahoma City, Oklahoma, United States
Digestive Disease Specialists /ID# 170772
🇺🇸Oklahoma City, Oklahoma, United States
Centex Studies, Inc. - Houston /ID# 201218
🇺🇸Houston, Texas, United States
Clinical Associates in Research Therapeutics of America, LLC /ID# 161307
🇺🇸San Antonio, Texas, United States
Southern Star Research Institute, LLC /ID# 168772
🇺🇸San Antonio, Texas, United States
Virginia Mason - Seattle Orthapedics /ID# 155577
🇺🇸Seattle, Washington, United States
Phoenix VA Health Care System /ID# 162261
🇺🇸Phoenix, Arizona, United States
University of Miami /ID# 155011
🇺🇸Miami, Florida, United States
Vista Health Research, LLC /ID# 212828
🇺🇸Miami, Florida, United States
ITB Research /ID# 161278
🇺🇸Miami, Florida, United States
Coral Research Clinic /ID# 158330
🇺🇸Miami, Florida, United States
CTCenter MaVe s.r.o. /ID# 163215
🇨🇿Olomouc, Czechia
NH Hospital a.s. /ID# 211073
🇨🇿Praha, Czechia
Lyell McEwin Hospital /ID# 211364
🇦🇺Elizabeth Vale, South Australia, Australia
Digestive Disease Consultants, A Division of Arizona Digestive Health, P.C /ID# 211882
🇺🇸Tempe, Arizona, United States
The Ohio State University /ID# 164706
🇺🇸Columbus, Ohio, United States
University of Arizona /ID# 158305
🇺🇸Tucson, Arizona, United States
UC San Diego Health Systems /ID# 155576
🇺🇸La Jolla, California, United States
Southern California Res. Ctr. /ID# 211989
🇺🇸Coronado, California, United States
United Medical Doctors /ID# 207887
🇺🇸Los Alamitos, California, United States
Gastrointestinal Biosciences Clinical Trials, LLC /ID# 162655
🇺🇸Los Angeles, California, United States
United Medical Doctors - Murrieta /ID# 158278
🇺🇸Murrieta, California, United States
Rocky Mountain Pediatric Gastroenterology /ID# 207171
🇺🇸Lone Tree, Colorado, United States
Western Connecticut Medical Group /ID# 165874
🇺🇸Danbury, Connecticut, United States
Seffner Premier Health Care, PA /ID# 162259
🇺🇸Brandon, Florida, United States
Universal Axon Clinical Research /ID# 165426
🇺🇸Doral, Florida, United States
South Lake Pain Institute, Inc /ID# 162798
🇺🇸Clermont, Florida, United States
Clinical Research of West Florida, Inc /ID# 205864
🇺🇸Clearwater, Florida, United States
Omega Research Maitland, LLC /ID# 171080
🇺🇸DeBary, Florida, United States
Alliance Medical Research /ID# 163834
🇺🇸Lighthouse Point, Florida, United States
South Florida Research Ph I-IV, Inc. /ID# 161825
🇺🇸Miami, Florida, United States
Advanced Research Institute, Inc /ID# 161973
🇺🇸New Port Richey, Florida, United States
Atlanta Gastro Assoc /ID# 154755
🇺🇸Atlanta, Georgia, United States
Northwestern University Division of GI/Hepatology /ID# 158250
🇺🇸Chicago, Illinois, United States
Gastroenterology Associates of Central Georgia, LLC /ID# 154865
🇺🇸Macon, Georgia, United States
The University of Chicago Medical Center /ID# 157113
🇺🇸Chicago, Illinois, United States
Southwest Gastroenterology /ID# 164764
🇺🇸Oak Lawn, Illinois, United States
NorthShore University HealthSystem /ID# 158254
🇺🇸Evanston, Illinois, United States
Gastroenterology Associates LLC - Jefferson Hwy /ID# 161970
🇺🇸Baton Rouge, Louisiana, United States
Cotton-O'Neil Clinical Res Ctr /ID# 154753
🇺🇸Topeka, Kansas, United States
University of Kentucky Chandler Medical Center /ID# 157109
🇺🇸Lexington, Kentucky, United States
Houma Digestive Health Special /ID# 158253
🇺🇸Houma, Louisiana, United States
Louisana Research Center, LLC /ID# 162239
🇺🇸Shreveport, Louisiana, United States
Gastro Center of Maryland /ID# 164766
🇺🇸Columbia, Maryland, United States
MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 154846
🇺🇸Chevy Chase, Maryland, United States
Center for Digestive Health /ID# 154697
🇺🇸Troy, Michigan, United States
Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinic /ID# 161267
🇺🇸Wyoming, Michigan, United States
Las Vegas Medical Research /ID# 160167
🇺🇸Las Vegas, Nevada, United States
NY Scientific /ID# 158272
🇺🇸Brooklyn, New York, United States
Intercity Advanced Gastroentertology Center /ID# 215204
🇺🇸Fresh Meadows, New York, United States
Saratoga Schenectady Gastroenterology Associates - Burnt Hills /ID# 213446
🇺🇸Burnt Hills, New York, United States
Digestive Disease Care /ID# 211776
🇺🇸New Hyde Park, New York, United States
North Shore University Hospital /ID# 168734
🇺🇸New Hyde Park, New York, United States
NYU Langone Medical Center /ID# 160166
🇺🇸New York, New York, United States
Icahn School of Medicine at Mount Sinai - The Mount Sinai Medical Center /ID# 165610
🇺🇸New York, New York, United States
Columbia Univ Medical Center /ID# 167545
🇺🇸New York, New York, United States
Lenox Hill Hospital /ID# 168466
🇺🇸New York, New York, United States
DiGiovanna Institute for Medical Education & Research /ID# 171130
🇺🇸North Massapequa, New York, United States
Atrium Health Carolinas Medical Center /ID# 158364
🇺🇸Charlotte, North Carolina, United States
Vidant Multispecialty Clinic - Kinston /ID# 161109
🇺🇸Kinston, North Carolina, United States
Plains Clinical Research Center, LLC /ID# 169712
🇺🇸Fargo, North Dakota, United States
Cleveland Clinic Main Campus /ID# 209225
🇺🇸Cleveland, Ohio, United States
Tri-State Endoscopy /ID# 154939
🇺🇸Cincinnati, Ohio, United States
Wake Radiology UNC REX Healthcare - Raleigh Office /ID# 154891
🇺🇸Raleigh, North Carolina, United States
Optimed Research, Ltd. /ID# 167877
🇺🇸Columbus, Ohio, United States
Great Lakes Medical Research, LLC /ID# 201774
🇺🇸Mentor, Ohio, United States
Hometown Urgent Care and Resea /ID# 170447
🇺🇸Dayton, Ohio, United States
PennState Milton S.Hershey Med /ID# 154894
🇺🇸Hershey, Pennsylvania, United States
Digestive Disease Associates, LTD /ID# 208296
🇺🇸Wyomissing, Pennsylvania, United States
Gastro One /ID# 154757
🇺🇸Germantown, Tennessee, United States
East Tennessee Research Institute /ID# 168735
🇺🇸Johnson City, Tennessee, United States
Gastroenterology Associates, P.A. of Greenville /ID# 154919
🇺🇸Greenville, South Carolina, United States
Duplicate_Clinical Neuroscience Solutions, Inc /ID# 164179
🇺🇸Memphis, Tennessee, United States
Rapid City Medical Center - GI Research /ID# 163835
🇺🇸Rapid City, South Dakota, United States
Inquest Clinical Research /ID# 165696
🇺🇸Baytown, Texas, United States
TX Clinical Research Institute /ID# 159396
🇺🇸Arlington, Texas, United States
Texas Digestive Disease Consultants /ID# 209781
🇺🇸Cedar Park, Texas, United States
Texas Digestive Disease Consultants /ID# 209945
🇺🇸Cedar Park, Texas, United States
DHAT Research Institute /ID# 158199
🇺🇸Garland, Texas, United States
Universitaetsklinikum St. Poelten /ID# 166423
🇦🇹Sankt Poelten, Niederoesterreich, Austria
HP Clinical Research /ID# 162992
🇺🇸Bountiful, Utah, United States
Footscray Hospital /ID# 211362
🇦🇺Footscray, Victoria, Australia
Duplicate_LKH-Univ. Klinikum Graz /ID# 158134
🇦🇹Graz, Steiermark, Austria
ULB Hospital Erasme /ID# 157386
🇧🇪Brussels, Bruxelles-Capitale, Belgium
Imelda Ziekenhuis /ID# 157381
🇧🇪Bonheiden, Belgium
AZ Maria Middelares /ID# 212871
🇧🇪Gent, Belgium
AZ Groeninge /ID# 212571
🇧🇪Kortrijk, Belgium
University Clinical Centre of the Republic of Srpska /ID# 165018
🇧🇦Banja Luka, Republika Srpska, Bosnia and Herzegovina
Clinical Center University of Sarajevo /ID# 165132
🇧🇦Sarajevo, Bosnia and Herzegovina
Acibadem City Clinic UMHAT Tokuda /ID# 165698
🇧🇬Sofia, Bulgaria
UMHAT Tsaritsa Joanna - ISUL /ID# 211241
🇧🇬Sofia, Bulgaria
University of Alberta - Zeidler Ledcor Centre /ID# 157100
🇨🇦Edmonton, Alberta, Canada
MHAT Trakia /ID# 201665
🇧🇬Stara Zagora, Bulgaria
Centro de Investigaciones Clínicas Viña del Mar /ID# 203585
🇨🇱Viña del Mar, Valparaíso, Chile
QEII - Health Sciences Centre /ID# 157089
🇨🇦Halifax, Nova Scotia, Canada
Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 210842
🇨🇳Shanghai, Shanghai, China
Servicio de Salud Occidente Hospital San Juan de Dios /ID# 171121
🇨🇱Santiago, Region Metropolitana De Santiago, Chile
Klinicki bolnicki centar Split /ID# 157705
🇭🇷Split, Splitsko-dalmatinska Zupanija, Croatia
Axon Clinical, s.r.o. /ID# 163216
🇨🇿Praha, Czechia
Sjællands Universitetshospital, Roskilde /ID# 155537
🇩🇰Roskilde, Sjælland, Denmark
Aalborg Universitets Hospital /ID# 160685
🇩🇰Aalborg, Denmark
Internal Medicine Department, Faculty of Medicine, AinShams University /ID# 158630
🇪🇬Cairo, Egypt
Odense Universitets Hospital /ID# 155536
🇩🇰Odense C, Denmark
CHU Bordeaux - Hopital Haut Lévêque /ID# 162546
🇫🇷Pessac CEDEX, Gironde, France
HCL - Hôpital Lyon Sud /ID# 162548
🇫🇷Pierre Benite CEDEX, Auvergne-Rhone-Alpes, France
CHRU Lille - Hopital Claude Huriez /ID# 162547
🇫🇷Lille, Hauts-de-France, France
Hapital Beaujon /ID# 166287
🇫🇷Clichy, Ile-de-France, France
Evangelisches Krankenhaus Kalk /ID# 212724
🇩🇪Cologne, Nordrhein-Westfalen, Germany
Universitatsklinikum Mannheim /ID# 162026
🇩🇪Mannheim, Baden-Wuerttemberg, Germany
Krankenhaus Waldfriede /ID# 212729
🇩🇪Berlin-Zehlendorf, Germany
Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 159338
🇩🇪Kiel, Schleswig-Holstein, Germany
Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 212892
🇩🇪Berlin, Germany
Medizinische Hochschule Hannover /ID# 162027
🇩🇪Hannover, Germany
Medizinisches Versorgunszentrum Dachau /ID# 211550
🇩🇪Dachau, Germany
Asklepios Westklinikum Hamburg /ID# 159336
🇩🇪Hamburg, Germany
University General Hospital of Heraklion PA.G.N.I /ID# 157417
🇬🇷Heraklion, Kriti, Greece
Duplicate_Gastro-Praxis Wiesbaden /ID# 159335
🇩🇪Wiesbaden, Germany
General Hospital of Chest Diseases of Athens SOTIRIA /ID# 170905
🇬🇷Athens, Attiki, Greece
Soroka University Medical Center /ID# 157789
🇮🇱Be'er Sheva, HaDarom, Israel
University Hospital Galway /ID# 157570
🇮🇪Galway, Ireland
Hadassah Medical Center-Hebrew University /ID# 171062
🇮🇱Jerusalem, Israel
Tel Aviv Sourasky Medical Center /ID# 157787
🇮🇱Tel Aviv-Yafo, Tel-Aviv, Israel
Sheba Medical Center /ID# 171059
🇮🇱Ramat Gan, Tel-Aviv, Israel
Hanyang University Guri Hospital /ID# 163351
🇰🇷Guri, Gyeonggido, Korea, Republic of
Istituto Clinico Humanitas /ID# 155658
🇮🇹Rozzano, Milano, Italy
CHA Bundang Medical center CHA University /ID# 163377
🇰🇷Seongnam si, Gyeonggido, Korea, Republic of
Academisch Medisch Centrum /ID# 157953
🇳🇱Amsterdam, Netherlands
Investigacion Biomedica para el Desarrollo de Farmacos, S.A. de C.V. /ID# 170766
🇲🇽Zapopan, Jalisco, Mexico
Dunedin Hospital /ID# 167215
🇳🇿Dunedin, Otago, New Zealand
Elisabeth Tweesteden Ziekenhuis /ID# 163620
🇳🇱Tilburg, Netherlands
JM Research SC /ID# 170762
🇲🇽Cuernavaca, Morelos, Mexico
Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie /ID# 209980
🇵🇱Lublin, Lubelskie, Poland
H-T. Centrum Medyczne - Endoterapia /ID# 212458
🇵🇱Tychy, Slaskie, Poland
Hospital Beatriz Ângelo /ID# 207758
🇵🇹Loures, Portugal
Hospital Garcia de Orta, EPE /ID# 160688
🇵🇹Almada, Portugal
Centro Hospitalar Universitario Lisboa Central, EPE - Hospital dos Capuchos /ID# 160677
🇵🇹Lisboa, Portugal
Centro Hospitalar Universitário de Lisboa Norte, EPE - Hospital de Santa Maria /ID# 160741
🇵🇹Lisboa, Portugal
Institutul Clinic Fundeni /ID# 170890
🇷🇴Sector 2, Bucuresti, Romania
Centro Hosp de Tondela-Viseu /ID# 160731
🇵🇹Viseu, Portugal
Duplicate_Perm state medical university n.a. E.A. Vagner /ID# 207438
🇷🇺Perm, Permskiy Kray, Russian Federation
Kuzbass Regional Clinical Hospital /ID# 200707
🇷🇺Kemerovo, Kemerovskaya Oblast, Russian Federation
Professor Pasechnikov Gastroenterology and Pankreatology clinic /ID# 200701
🇷🇺Stavropol, Stavropol Skiy Kray, Russian Federation
Regional Clinical Hospital #1 /ID# 200708
🇷🇺Tyumen, Tyumenskaya Oblast, Russian Federation
National Medical Research Center of Coloproctology n.a. A. N. Ryzhikh /ID# 204806
🇷🇺Moscow, Russian Federation
Alliance Biomedical Ural Group /ID# 200703
🇷🇺Izhevsk, Udmurtskaya Respublika, Russian Federation
City Clinical Hospital No. 31 /ID# 208865
🇷🇺St. Petersburg, Russian Federation
Military Medical Academy /ID# 156963
🇷🇸Belgrade, Beograd, Serbia
Ulyanovsk Regional Clinical Hospital /ID# 200700
🇷🇺Ulyanovsk, Russian Federation
Clinical Hosp Center Zvezdara /ID# 156956
🇷🇸Belgrade, Beograd, Serbia
Clinical Center Vojvodina /ID# 156958
🇷🇸Novi Sad, Vojvodina, Serbia
Clinical Hospital Center Dr Dragisa Misovic - Dedinje /ID# 212798
🇷🇸Belgrade, Serbia
University Children's Hospital 'Tirsova' /ID# 211480
🇷🇸Belgrade, Serbia
Univerzitna nemocnica Martin /ID# 163205
🇸🇰Martin, Slovakia
KM Management, spol. s.r.o. /ID# 206762
🇸🇰Nitra, Slovakia
GASTRO I., s.r.o. /ID# 156455
🇸🇰Presov, Slovakia
Kingsbury Hospital /ID# 171158
🇿🇦Cape Town, Western Cape, South Africa
Wits Clinical Research Site /ID# 171169
🇿🇦Johannesburg, Gauteng, South Africa
Spoke Research Inc /ID# 171172
🇿🇦CAPE TOWN Milnerton, Western Cape, South Africa
Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 157534
🇪🇸Ferrol, A Coruna, Spain
Consorci Corporacio Sanitaria Parc Tauli Sabadell /ID# 159234
🇪🇸Sabadell, Barcelona, Spain
Private Practice Dr MN Rajabally /ID# 171159
🇿🇦Cape Town, Western Cape, South Africa
Hospital Clinic de Barcelona /ID# 157533
🇪🇸Barcelona, Spain
Hospital Universitario Basurto /ID# 205188
🇪🇸Bilbao, Vizcaya, Spain
Hospital General Universitario Gregorio Maranon /ID# 161144
🇪🇸Madrid, Spain
Hospital Universitario La Paz /ID# 159232
🇪🇸Madrid, Spain
Hospital Universitario y Politecnico La Fe /ID# 157537
🇪🇸Valencia, Spain
Hospital Universitario Virgen Macarena /ID# 159966
🇪🇸Sevilla, Spain
Hospital Clinico Universitario de Valencia /ID# 209699
🇪🇸Valencia, Spain
Hospital Clinico Universitario de Salamanca /ID# 157539
🇪🇸Salamanca, Spain
Hospital Universitario Miguel Servet /ID# 157538
🇪🇸Zaragoza, Spain
Taipei Veterans General Hosp /ID# 212711
🇨🇳Taipei City, Taiwan
National Cheng Kung University Hospital /ID# 160129
🇨🇳Tainan City, Taiwan
Duplicate_Transcarpathian Regional Clin. /ID# 167958
🇺🇦Uzhhorod, Ukraine
NHS Greater Glasgow and Clyde /ID# 202314
🇬🇧Glasgow, Scotland, United Kingdom
Ashford and St Peter's Hospitals NHS Foundation Trust /ID# 207938
🇬🇧Chertsey, Surrey, United Kingdom
Cambridge University Hospitals NHS Foundation Trust /ID# 158037
🇬🇧Cambridge, United Kingdom
University Hospitals Birmingham NHS Foundation Trust /ID# 157577
🇬🇧Birmingham, United Kingdom
Barnsley Hospital NHS Foundation Trust /ID# 202772
🇬🇧Barnsley, United Kingdom
NHS Lothian /ID# 207446
🇬🇧Edinburgh, United Kingdom
Hull University Teaching Hospitals NHS Trust /ID# 158759
🇬🇧Hull, United Kingdom
The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 163889
🇬🇧Newcastle Upon Tyne, United Kingdom
Oxford University Hospitals NHS Foundation Trust /ID# 158039
🇬🇧Oxford, United Kingdom
King's College Hospital NHS Foundation Trusts /ID# 158758
🇬🇧London, United Kingdom
Duplicate_Northern Care Alliance NHS Group /ID# 207765
🇬🇧Salford, United Kingdom
Peak Gastroenterology Associates, PC /ID# 165832
🇺🇸Colorado Springs, Colorado, United States
Duplicate_Klinicka bolnica Dubrava Zagreb /ID# 157719
🇭🇷Zagreb, Grad Zagreb, Croatia
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclaw /ID# 212534
🇵🇱Wroclaw, Poland
Kyiv Municipal Clinical Hospital #18 /ID# 162527
🇺🇦Київ, Ukraine
Endoscopic Research, Inc. /ID# 205903
🇺🇸Orlando, Florida, United States
Clinical Research Trials of Florida, Inc. /ID# 201606
🇺🇸Tampa, Florida, United States
Medical University of South Carolina /ID# 212859
🇺🇸Charleston, South Carolina, United States
University of Louisville /ID# 210523
🇺🇸Louisville, Kentucky, United States
Nola Research Works, LLC /ID# 161271
🇺🇸New Orleans, Louisiana, United States
Delricht Research /ID# 206567
🇺🇸New Orleans, Louisiana, United States
Hunter Holmes McGuire VA Medical Center /ID# 159977
🇺🇸Richmond, Virginia, United States
Emeritus Research /ID# 213510
🇦🇺Camberwell, Victoria, Australia
Fraser Clinical Trials Inc /ID# 159057
🇨🇦New Westminster, British Columbia, Canada
Medicor Research Inc /ID# 157151
🇨🇦Sudbury, Ontario, Canada
Toronto Digestive Disease Asso /ID# 157159
🇨🇦Vaughan, Ontario, Canada
Sir Run Run Shaw Hospital Zhejiang University School of Medicine /ID# 210626
🇨🇳Hangzhou, Zhejiang, China