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Mechanism and Efficacy of Rehabilitation Approaches

Not Applicable
Completed
Conditions
Cerebrovascular Accidents
Registration Number
NCT00564005
Lead Sponsor
Chang Gung Memorial Hospital
Brief Summary

Identify the possible mechanisms and the relative effectiveness of existing rehabilitation approaches that target upper extremity deficits of stroke patients on the ground that these approaches are based on neuroplasticity principles and sound motor control theories.

Detailed Description

Comparisons of constraint-induced therapy (CIT) vs. bilateral arm training (BIT)vs. combined therapy were made. Stroke patients will receive one of these three approaches and be evaluated pre- and post-treatment. the treatment will last 3 weeks and 5 days per week. The evaluation will include clinical measures of motor function, ADL, and quality of life, kinematic performance, and activation patterns of cortex.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
90
Inclusion Criteria
  • a first-ever clinical cerebrovascular accident patients
  • at least 6 months post-stroke onset
  • premorbid right-hand dominance
  • demonstration of Brunnstrom stage III of the affected upper extremity
  • no excessive spasticity in the joints of the affected upper extremity
Exclusion Criteria
  • a score of less than 24 on the Mini Mental State Exam
  • poor physical conditions that would interfere with participation
  • excessive pain in any joint that might limit participation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Cortical reorganization and kinematic analysis2008-2010
Secondary Outcome Measures
NameTimeMethod
clinical measures at the impairment, activity, participation levels2008-2010

Trial Locations

Locations (1)

Chang Gung Memorial Hospital

🇨🇳

Kwei-shan, Toayuan county, Taiwan

Chang Gung Memorial Hospital
🇨🇳Kwei-shan, Toayuan county, Taiwan

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