Is the Efficacy of Epidural Steroid Injections Related to the Different Volume Injections? :A Randomised, Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Triamcinolone
- Conditions
- Pain
- Sponsor
- Neslihan Uztüre
- Enrollment
- 75
- Primary Endpoint
- VAS (visual analog scale) [O= no pain, 10 = unbearable pain]
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
This study was aimed to investigate the impact of using different epidural volumes.
Patients with acute discogenic pain were included in the study.
Detailed Description
Objectives: This study was aimed to investigate the impact of using different epidural volumes. Methods: Seventy five patients with acute discogenic pain were included in the study.The patients were randomly assigned to three groups. All patients received a single epidural dose of triamcinolone \[80 mg\] and 12.5 mg bupivacaine combination. The patients in Group 1, Group 2 and Group 3 received a volume of 10 mL, 15 mL, and 20 mL by epidural injections, respectively. The efficacy of treatment was assessed with VAS (visual analog scale) \[O= no pain, 10 = unbearable pain\], SLET(straight leg elevation test) \[0° = worst, 85° = best\], and Oswestry Disability Index; ODI \[0% to 20%:minimal disability , 80% to 100%:bed bound patients\] before and 2 weeks after the EPSI.
Investigators
Neslihan Uztüre
assistant proffessor
Yeditepe University Hospital
Eligibility Criteria
Inclusion Criteria
- •acute discogenic pain with less than three months duration not responding to other modalities of conservative management \[NSAIDs, physiotherapy, bracing, etc.\],
- •radiological disc bulging accompanying unilateral root impingement symptoms,
- •an Oswestry daily activity score more than 20 percent, and
- •resistance to treatment.
Exclusion Criteria
- •Patients with bilateral root impingement symptoms, neurological deficits, and/or history of previous lumbar disc surgery, severe cardiac, pulmonary, gastrointestinal, renal diseases, glaucoma, urinary retention, and/or known allergy to the drugs used in the study were excluded from the study.
Arms & Interventions
Epidural Volume 10mL
Epidural Volume 10mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 10mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Triamcinolone
Epidural Volume 10mL
Epidural Volume 10mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 10mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Epidural Volume
Epidural Volume 10mL
Epidural Volume 10mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 10mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Bupivacaine
Epidural Volume 15mL
Epidural Volume 15mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 15 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Triamcinolone
Epidural Volume 15mL
Epidural Volume 15mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 15 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Epidural Volume
Epidural Volume 15mL
Epidural Volume 15mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 15 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Bupivacaine
Epidural Volume 20mL
Epidural Volume 20mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 20 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Triamcinolone
Epidural Volume 20mL
Epidural Volume 20mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 20 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Epidural Volume
Epidural Volume 20mL
Epidural Volume 20mL, Intervention: Drug: Triamcinolone 80 mg Intervention: Drug: Epidural Volume 20 mL Intervention: Drug: Bupivacaine 12.5mg
Intervention: Bupivacaine
Outcomes
Primary Outcomes
VAS (visual analog scale) [O= no pain, 10 = unbearable pain]
Time Frame: 2 weeks
Oswestry Disability Index; ODI [0% to 20%:minimal disability , 80% to 100%:bed bound patients]
Time Frame: 2 weeks
SLET(straight leg elevation test) [0° = worst, 85° = best]
Time Frame: 2 weeks