Reducing Healthcare Costs in Older Adults by Deprescribing Unnecessary, Harmful, and Costly Medications
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Polypharmacy
- Sponsor
- The University of Texas Health Science Center, Houston
- Enrollment
- 419
- Locations
- 1
- Primary Endpoint
- Healthcare Cost
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The purpose of the study is to implement a pharmacist-led deprescribing intervention for adults 65 and older taking 10 or more medications at University of Texas (UT) Physicians clinics and to assess the effect of the pharmacist intervention on the incidence of adverse drug reactions, emergency room visits, and hospitalizations as well as costs to the patient and to the healthcare system in adults 65 and older taking 10 or more medications treated at UT Physicians.
Investigators
Holly M Holmes
Associate Professor
The University of Texas Health Science Center, Houston
Eligibility Criteria
Inclusion Criteria
- •taking 10 or more regular medications
Exclusion Criteria
- •not receiving primary care at UT Physicians
Outcomes
Primary Outcomes
Healthcare Cost
Time Frame: 12 months post enrollment
Healthcare cost based on utilization of clinic visits, emergency room visits, and hospitalizations, based on patient report with specific costs obtained when possible from the Health Information Exchange.
Adverse Drug Reactions
Time Frame: 12 months post enrollment
Patient-reported side effects and adverse events potentially attributable to medication, rated for the likelihood of ADR by an independent reviewer based on the Naranjo algorithm.
Adverse Drug Reactions (ADR)
Time Frame: 3 months post enrollment
Patient-reported side effects and adverse events potentially attributable to medication, rated for the likelihood of ADR by an independent reviewer based on the Naranjo algorithm.
Secondary Outcomes
- Medication cost(12 months post enrollment)
- Medication use(At enrollment)
- QOL(12 months post enrollment)