Tinzaparin in pediatric intensive care patients
- Conditions
- - Antistolling/anticoagulation- Tinzaparine/tinzaparin- Anti-Xa spiegels/anti-Xa levels
- Registration Number
- NL-OMON26406
- Lead Sponsor
- eiden University Medical Center (LUMC), Department of Pediatric Intensive Care
- Brief Summary
Roeleveld P.P. et al; Higher Tinzaparin Dosing Is Needed to Achieve Target Anti-Xa Levels in Pediatric Cardiac Intensive Care Patients. Pediatric Critical Care Medicine, January 2016.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Patients on the pediatric intensive care unit with tinzaparin as therapeutic anticoagulation
Exclusion Criteria
- Patients with tinzaparin as profylactic anticoagulation
- Patients with an coagulation disorder
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Anti-Xa levels<br /><br>- Time till adequate anti-Xa levels<br /><br>- Doses that lead to adequate anti-Xa levels<br>
- Secondary Outcome Measures
Name Time Method - Influence of renal function<br /><br>- Influence of hepatic function<br /><br>- Comedication<br /><br>- Presence of edema<br /><br>- Disease severity (PRISM score)