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Clinical Trials/NCT05345704
NCT05345704CompletedNot Applicable

Simulation-based Comparative Study on Efficiency of Ventilation During Paediatric Cardiopulmonary Resuscitation in Health Care Professionals and Lay Rescuers

Brno University Hospital1 site in 1 country86 target enrollmentStarted: April 28, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
86
Locations
1
Primary Endpoint
Initial ventilation effectivity

Study Overview

Brief Summary

The aim of this study is to gather data to support beginning the pediatric cardiopulmonary resuscitation (CPR) with 5 initial breaths. The group of health care professionals and the group lay rescuers will be asked to perform cardiopulmonary resuscitation (CRP) on 2 pediatric simulation mannequins (the 3-month-old infant, 5 kg, and the 5-year-old child, 25 kg) and the effectiveness of initial ventilation attempts will be evaluated.

Detailed Description

There is a lack of knowledge on the efficiency of ventilation during simulated and real cardiopulmonary resuscitation of children and infants. The ventilations should be an integral part of pediatric resuscitation as recommended by European Resuscitation Council (ERC) because the respiratory and other secondary causes with oxygen depletion are common causes of cardiac arrest in children. However, the effectiveness and quality of ventilation are rarely studied and ERC guidelines to start ventilation with 5 initial breaths in pediatric CPR are based on the experts´ opinion. This study evaluates ventilation efficiency during simulated pediatric cardiopulmonary resuscitation performed by 2 different groups of potential rescuers - physicians, nurses- representing the advanced life support and lay rescuers- representing the basic life support algorithm. The primary aim of this study is to evaluate the number of effective breaths (define as a visible chest rise) during 5 initial breaths attempts of simulated pediatric cardiopulmonary resuscitation. Secondary outcomes include subanalysis of the effectiveness of two initial breaths attempts, defined as a visible chest rise, time to first effective breath, breath volume delivered during 5 initial breaths, and breaths during CPR. The appropriate volume would be considered 6-10 mL/kg (i.e. 30 - 50 mL in infant and 125- 250 mL in the child). The data will be obtained before and after standardized simulation training in both groups. For lay rescuers, the dispatcher-assisted CPR will be simulated. For the health care professionals, basic equipment will be available and expected to be used (correct size mask and bag-mask ventilation).

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Volunteer participants - lay rescuers
  • •Health care professionals performing simulated CPR

Exclusion Criteria

  • •not willing to participate

Outcomes

Primary Outcomes

Initial ventilation effectivity

Time Frame: During 90 seconds of life support

Number of ventilations that are effective out of the first 5 attempts in each group. Defined as breath that has the ability to elevate the chest

Secondary Outcomes

  • Delay in ventilation(During 90 seconds of life support)
  • Initial 2 breaths effectivity(During 90 seconds of life support)
  • Initial ventilation adequacy(During 90 seconds of life support)
  • Ventilation volume during initial breaths(During 90 seconds of life support)
  • Delay in CPR(During 90 seconds of life support)
  • CPR description(During 90 seconds of life support)

Investigators

Sponsor
Brno University Hospital
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Petr Štourač, MD

Clinical Professor

Brno University Hospital

Study Sites (1)

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