Antibiotic Prescription in Children Hospitalized for Community-acquired Pneumonia
- Conditions
- Community Acquired Pneumonia in ChildrenAntibiotic Stewardship
- Interventions
- Other: Antibiotic treatmentOther: No antibiotic treatment
- Registration Number
- NCT04681339
- Lead Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
- Brief Summary
A study to observe how often antibiotics are prescribed in children hospitalized for pneumonia and how doctors decide if a child needs antibiotics or not. Parent satisfaction will also be recorded.
- Detailed Description
An observational study to document the antibiotic treatment rate of children hospitalized for community acquired pneumonia at a pediatric department with longstanding practice of restrictive antibiotic prescribing. Patients will be enrolled consecutively and treated according to in-house standard operating procedure. Antibiotic treatment rate, severity of disease and medical complication rate in antibiotic and non-antibiotic managed children, frequency of predefined factors in physician decision making on antibiotic use, and parental satisfaction will be recorded. Parents will be contacted at least 4 weeks after discharge to inquire about recurrence or readmission.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 200
- Hospital admission at the pediatric department of the Filderklinik or at the pediatric department of the Herdecke Community Hospital
- Admission diagnosis pneumonia or pneumonia diagnosis within 48 hours of admission
- Written informed consent by care giver
- All inclusion criteria have to be fulfilled
- Insufficient knowledge of German to understand the written patient information and questionnaire
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Pneumonia with antibiotics Antibiotic treatment Children with non-severe community acquired pneumonia and fever: managed with antibiotics Pneumonia without antibiotics No antibiotic treatment Children with non-severe community acquired pneumonia and fever: managed without antibiotics
- Primary Outcome Measures
Name Time Method Antibiotic treatment rates in hospitalized children with non-severe community-acquired pneumonia and fever During hospitalization, an average of 7 days Rates of treatment with and without antibiotics during hospitalization
- Secondary Outcome Measures
Name Time Method Number of medical complications During hospitalization, an average of 7 days Medical complications defined as a) admission to intensive care, mechanical ventilation, transfer to tertiary car center OR b) pleural effusion or empyema, pneumothorax, lung abscess, bronchopleural fistula, necrotizing pneumonia, acute respiratory failure, infectious complication (meningitis, septic shock).
Factors in physician decision making on antibiotic prescription During hospitalization, an average of 7 days Physician questionnaire (closed-ended questions)
Parental satisfaction At discharge, assessing the entire duration of the hospital stay, an average of 7 days Parental satisfaction questionnaire (closed-ended questions)
Number of children with relevant comorbidity During hospitalization, an average of 7 days Co-morbidities that may affect decision on antimicrobial use: a) chronic conditions (e.g. neurological conditions such as cerebral palsy, Down syndrome; or chronic respiratory conditions such as asthma, cystic fibrosis; or heart conditions). b) acute infectious comorbidities: bronchiolitis, otitis media, urinary tract infection, confirmed influenza virus or Respiratory Syncytial Virus or SARS-CoV2.
Days of supplemental oxygen use During hospitalization, an average of 7 days Oxygen therapy for O2 saturation \<92%
Use of antipyretic medications During hospitalization, an average of 7 days Number of doses of paracetamol or ibuprofen during hospitalization
Number of complementary medicine medications used per child During hospitalization, an average of 7 days Number of complementary medication during hospitalization
Hospitalization duration At discharge, assessing the entire duration of the hospital stay, an average of 7 days Number of hospitalization days
Number of readmissions for pneumonia or new pneumonia recurrences within 4 weeks of hospital discharge 4 weeks after end of hospitalization New hospital admission for pneumonia; treatment requiring recurrence of pneumonia
Trial Locations
- Locations (2)
Herdecke Community Hospital
🇩🇪Herdecke, Nordrhein-Westfalen, Germany
Die Filderklinik
🇩🇪Filderstadt, Baden-Württemberg, Germany