Characterization of the Nutritional Status in the Patient With Liver Cirrhosis
Not Applicable
Completed
- Conditions
- Sarcopenia
- Interventions
- Dietary Supplement: Branched chain amino acids (BRCA)
- Registration Number
- NCT04073693
- Lead Sponsor
- Puerta de Hierro University Hospital
- Brief Summary
In the subgroup of patients with sarcopenia, regardless of their body mass index, we want to verify the real impact of nutritional supplements with branched chain amino acids on the standard treatment based on nutritional intervention and physical exercise.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
- Cirrhotic patients with sarcopenia in abdominal CT.
Exclusion Criteria
- chronic renal failure or being on hemodialysis
- active hepatitis B or C virus infection
- active alcohol abuse
- coinfection with human immunodeficiency virus
- renal or previous liver transplantation
- history of neoplasia requiring chemotherapy or radiotherapy
- hepatocellular carcinoma outside of Milan criteria
- TIPs
- unwillingness to participate in the study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Branched chain amino acids (BRCA) They only were on standard treatment based on nutritional intervention and physical exercise. BRCA Branched chain amino acids (BRCA) They were in treatment with BRCA and standard treatment based on nutritional intervention and physical exercise.
- Primary Outcome Measures
Name Time Method Change of muscle mass in patients with sarcopenia 12 weeks To assess whether to add to dietary and physical activity recommendations, nutritional supplements with BRCA under usual clinical conditions can lead to a greater change of muscle mass in patients with sarcopenia
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Jose Luis Calleja
🇪🇸Majadahonda, Madrid, Spain