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Evaluation of patients with dyssynergic defecation after biofeedback therapy by MR defecography

Not Applicable
Conditions
Chronic costipation and dyssynergic defecation.
Disorder of muscle, unspecified
Registration Number
IRCT2015011020011N1
Lead Sponsor
Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
22
Inclusion Criteria

The Patients participate in this study, with chronic constipation who fulfill Rome diagnostic criteria” for functional constipation for at least 12 weeks: they need to strain in defecation, have lumpy or hard stools, sensation of incomplete evacuation, and need manual maneuvers to facilitate defecation in more than 1/4 of bowel movements. They have a dyssynergic pattern of defecation. The patients also have diagnostic testing evidence (anorectal manometry or defecography or balloon expulsion test) of dyssynergic defecation. The diagnosis of paradoxical contraction of puborectalis muscle during straining is established by digital rectal examination. Patients were excluded from the study if they had previous anorectal surgery, anorectal tumors, or structural anorectal disorders, which needed operation intervention. Other exclusion criteria were significant cardiovascular, respiratory, neurologic, psychiatric illnesses, sever psychological problems, or endocrine and metabolic diseases that could cause constipation

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Muscle function((Paradox index & perinal descend index ). Timepoint: before treatment and after its completion (3 months). Method of measurement: MR defecography.
Secondary Outcome Measures
NameTimeMethod
Symptomatic changes. Timepoint: before tretment and after its completion. Method of measurement: costipation scoring questionnaire.;The quality of life. Timepoint: before tretment and after its completion. Method of measurement: the culturally adapted version of Short Form-36.;Severity of depression. Timepoint: before tretment and after its completion. Method of measurement: , the culturally adapted version of Beck Depression Inventory questionnaires.
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