Feasibility trial of neoadjuvant chemotherapy with docetaxel,cisplatin and fluorouracil for clinical stage II/III esophageal carcinoma.
Phase 2
- Conditions
- esophageal neoplasm
- Registration Number
- JPRN-UMIN000002396
- Lead Sponsor
- Saitama Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1) Simultaneous or metachronous (within 5 years) double cancers , with the exception of intramucosal tumor curable with local therapy 2) Pregnant or lactating women or women of childbearing potential 3) Psychosis 4) Patients requiring systemic steroids medication 5) HBs antigen positive 6) Uncontrollable diabetes millutus 7) History of myocardial infarction or unstable angina pectoris or interstitial pneumonia or fibroid lung or severe emphysema 8) Active bacterial or fungous infection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of treatment completion
- Secondary Outcome Measures
Name Time Method Overall survival Progression free survival Resectability rate Adverse event Response rate