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Clinical Trials/ISRCTN30070325
ISRCTN30070325
Completed
未知

A randomized, prospective, pilot study comparing the efficacy of Selective Laser Trabeculoplasty versus Brimonidine tartrate 0.2%/Timolol maleate 0.5% (Combigan, Allergan Inc.) in lowering intraocular pressure as adjunct therapy in Primary Open Angle Glaucoma.

niversity of Pikeville Kentucky College of Optometry0 sites23 target enrollmentDecember 14, 2018
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ConditionsPrimary Open Angle GlaucomaEye Diseases

Overview

Phase
未知
Intervention
Not specified
Conditions
Primary Open Angle Glaucoma
Sponsor
niversity of Pikeville Kentucky College of Optometry
Enrollment
23
Status
Completed
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2019 Preprint results in https://doi.org/10.21203/rs.2.473/v1 (added 28/09/2021) 2021 Results article in http://dx.doi.org/10.24966/OCR-8887/100075 (added 28/09/2021)

Registry
who.int
Start Date
December 14, 2018
End Date
July 25, 2018
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Pikeville Kentucky College of Optometry

Eligibility Criteria

Inclusion Criteria

  • •1\. Uncontrolled primary open angle glaucoma
  • •2\. Open angle on gonioscopy
  • •3\. Aged 25 to 90 years
  • •4\. Currently taking a prostaglandin analog, but IOP not controlled with monotherapy

Exclusion Criteria

  • •1\. Best corrected visual acuity worse than 20/40 in the study eye (meaning 20/50 or worse)
  • •2\. Hx of angle closure or an occludable angle on gonioscopy
  • •3\. Untreated IOP less than or equal to 21 mmHg
  • •4\. Patients who have used a second IOP lowering medication in the past 2 months
  • •5\. Angle recession on gonioscopy
  • •6\. Pseudoexfoliation glaucoma
  • •7\. Pigment dispersion glaucoma
  • •8\. Prior incisional glaucoma surgery
  • •9\. Prior Microinvasive Glaucoma Surgery (MIGS, istent, Endocyclophotocoagulation)
  • •10\. Previous SLT or Argon Laser Trabeculoplasty (ALT)

Outcomes

Primary Outcomes

Not specified

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