NL-OMON39379
已完成
不适用
Disrupting the rythm of depression: effectiveness and cost-effectiveness and mediating factors of preventive cognitive therapy, with or without antidepressants and compared to antidepressants alone, in the prevention of recurrent major depressive disorder. - Disrupting the rhythm of depression
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- major depressive disorder
- 发起方
- niversitair Medisch Centrum Groningen
- 入组人数
- 276
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Patients with major depressive disorder (DSM\-IV) with at least two previous depressive episodes in the past five years.
- •Last episode was treated succesfully with an antidepressant and the patient is still using that antidepressant at an adequate dose (recommended minimum dose according to Farmacotherapeutisch Kompas.
- •Currently in remission according to DSM\-IV criteria, for at least 8 weeks and no longer than 2 years.
- •A current score of \<10 in the Hamilton Rating Scale for Depression (HRSD).;New addition on 30\-7\-2012
- •All included participants are able to particpate in the additional study with the exception of women with a current pregnancy or recent delivery (\<6 months); in case of doubt the woman will not be included.
排除标准
- •\* Bipolar I of bipolar II disorder (indicated by previous or current manic or hypomanic episode (DSM\-IV)
- •\* serious neurological or somatic disorder (including organic brain damage) as possible cause of depression
- •\* alcohol or drug abuse during the last six months; alcohol or drug dependence during two years
- •\* comorbid anxiety disorder, necessitating additional treatment
- •\* ongoing or recent (\<6 months) psychotherapy (CT, CBT, IPT, etcetera) with a frequency of more than two times a month.
结局指标
主要结局
未指定
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