Daily Single Shot Adductor Canal Block Versus Continuous Adductor Canal Block After Total Knee Arthroplasty
- Conditions
- Postoperative Pain
- Interventions
- Procedure: Single shot adductor canal blockProcedure: Continuous adductor canal block
- Registration Number
- NCT05727137
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
This study will compare the analgesic efficacy of daily single-shot adductor canal block(ABC) versus continuous ACB after total knee arthroplasty (TKA).
- Detailed Description
Patients 19-75 years old, of ASA classification I-III scheduled for unilateral TKA, will be enrolled and randomized into two groups, single-shot ACB group and continuous ACB group. In both groups, participants will be administered a single-shot ACB immediately after the end of the operation. The single-shot ACB group will receive two separate single-shot ACBs, on the first and second postoperative day. A nerve block catheter will be placed in patients in the continuous ACB group, which will be connected to a patient-controlled analgesia pump until the second postoperative day. The primary outcome of this study is the average NRS pain score at rest from the end of surgery to 2 days after surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
- ASA classification I, II, III
- Patients scheduled for unilateral knee arthroplasty
- Anesthesia other than spinal anesthesia
- Chronic opioid use
- Uncontrolled diabetes of HbA1c>7.5
- Neuromuscular pathology of the ipsilateral leg
- Second-look knee arthroplasty
- Inability to communicate (e.g. dementia)
- Hypersensitivity to ropivacaine
- BMI > 40
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Single shot adductor canal block Single shot adductor canal block - Continuous adductor canal block Continuous adductor canal block -
- Primary Outcome Measures
Name Time Method Average NRS pain score at rest first 48h after end of surgery average of numerical rating scale (0: no pain, 10: worst imaginable pain) pain scores from 8 time points during 48h (+4h, +8h, +12h from end of surgery, 6AM, 2PM, 10PM of postoperative day 1, and 6AM and 2PM of postoperative day 2)
- Secondary Outcome Measures
Name Time Method Strengh of quadratus femoris muscle (unit: kgf) at 2PM on postoperative day 1 and 2 NRS pain score at rest at 10PM on postoperative day 1 10PM on postoperative day 1 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score at rest at +4h from end of surgery +4h from end of surgery numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at +4h from end of surgery +4h from end of surgery NRS pain score at rest at +8h from end of surgery +8h from end of surgery numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at +8h from end of surgery +8h from end of surgery numerical rating scale (0: no pain, 10: worst imaginable pain) pain score at rest at +12h from end of surgery +12h from end of surgery numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at +12h from end of surgery +12h from end of surgery Incidence of falls during hospital stay from end of surgery to 48h after surgery numerical rating scale (0: no pain, 10: worst imaginable pain) pain score at rest at 6AM on postoperative day 1 6AM on postoperative day 1 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at 6AM on postoperative day 1 6AM on postoperative day 1 NRS pain score at rest at 2PM on postoperative day 1 2PM on postoperative day 1 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at 10PM on postoperative day 1 10PM on postoperative day 1 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score during movement at 2PM on postoperative day 2 2PM on postoperative day 2 Postoperative range of motion of knee joint at 2PM on postoperative day 1 and 2 NRS pain score during movement at 2PM on postoperative day 1 2PM on postoperative day 1 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score at rest at 6AM on postoperative day 2 6AM on postoperative day 2 NRS pain score during movement at 6AM on postoperative day 2 6AM on postoperative day 2 numerical rating scale (0: no pain, 10: worst imaginable pain) pain score at rest at 2PM on postoperative day 2 2PM on postoperative day 2 Posteoperative opioid administration in morphine equivalents from end of surgery to 48h after surgery Incidence of catheter tip dislocation at 2PM on postoperative day 1 and 2 The catheter tip is considered to be dislocated if the catheter tip is located outside the adductor canal
Incidence of extravasation from catheter insertion site at 2PM on postoperative day 1 and 2 Incidence of sleep disturbance due to pain from end of surgery to postoperative day 2 Incidence of numbness of anterior thigh area at 2PM on postoperative day 1 and 2
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of