Evaluation of C-reactive protein in predicting conversion of laparoscopic cholecystectomy
Not Applicable
- Conditions
- Health Condition 1: K80- Cholelithiasis
- Registration Number
- CTRI/2019/03/017965
- Lead Sponsor
- Government Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other (Terminated)
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
1) All adult patients presenting with the clinical diagnosis of cholecystitis and cholelithiasis of either sex.
2) All patients willing to participate in the study.
Exclusion Criteria
1) Patients already planned for open cholecystectomy
2) Patients on drugs which alter the CRP levels
3) Patients with-
-BMI more than 30kg/m2
-HIV positive patients
-Autoimmune conditions (like rheumatoid
arthritis, lupus, inflammatory bowel disease)
-Inflammatory conditions (like pericarditis)
-Gallbladder or other GIT cancer
-Breast cancer
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate whether serum CRP can be used as a predictor or marker of conversion in patients undergoing elective laparoscopic cholecystectomyTimepoint: 1 year
- Secondary Outcome Measures
Name Time Method 1) The level of CRP at which conversion of laparoscopic to open cholecystectomy can be predicted <br/ ><br>2) The sensitivity, specificity and positive predictive value of CRP in predicting conversion to open cholecystectomy <br/ ><br>3) Whether raised serum CRP can predict difficult laparoscopy and its cut off value for the same.Timepoint: 1 year