To find out the effect of bone like material mixed with material obtained from patients own blood in gum diseases with evenly reduced bone height.

Not yet recruiting

Conditions: Chronic periodontitis,

Registration Number: CTRI/2021/02/031359

Lead Sponsor: Dr Swathy S

Brief Summary: The study titled evaluation of the efficacy of calcium phosphosilicate bioactive glass in combination with autologous platelet rich fibrin in the treatment of horizontal bone defects in periodontitis will be conducted in Vydehi Institute of Dental Sciences and Research Centre for a study period of 9 months. Periodontitis is a chronic inflammatory disease that causes loss of tooth attachment apparatus. one of the prominent signs of destructive periodontal disease is loss of alveolar bone support. In this loss of alveolar bone support horizontal bone loss is the most prominent. though the prevelance of horizontal bone loss is 92%, the available treatment modalities are only 2%. Thus the main aim of my study is evaluate the effect calcium phsphosilicate bioactive glass in combination with autologous platelet rich fibrin in the treatment of horizontal bone loss.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients diagnosed with stage II and III periodontitis according to 2017 World Workshop on the Classification of Periodontal and Peri-implant diseases and conditions Premolars and molars with a probing depth of â‰¥ 5mm to 8mm and a horizontal bone loss of 5mm or more from the CEJ to the alveolar crest in CBCT.

Exclusion Criteria

Medically compromised patients Teeth with grade III mobility Patients who underwent periodontal surgery in the past one year Smokers Pregnant and lactating women.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Probing pocket depth	9 months
Clinical attachment level	9 months
Height of bone assessed from CEJ to the alveolar crest obtained through Cone Beam Computed Tomography radiographic method	9 months
Width of the bone at the thinnest portion between the buccal / lingual and palatal plate in axial tomogram	9 months

Secondary Outcome Measures

Name	Time	Method
Plaque index	Gingival index

Trial Locations

Locations (1): Vydehi Institute of Dental Sciences and Research center
🇮🇳
Bangalore, KARNATAKA, India
Vydehi Institute of Dental Sciences and Research center
🇮🇳Bangalore, KARNATAKA, India
Dr Swathy S
Principal investigator
9946053866
swathyskumar91@yahoo.com