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临床试验/CTRI/2021/02/031359
CTRI/2021/02/031359尚未招募不适用

Evaluation of the Efficacy of Calcium Phosphosilicate Bioactive Glass in Combination with Autologous Platelet Rich Fibrin in the Treatment of Horizontal Bone Defects in Periodontitis- Randomized controlled trial with split mouth design

Dr Swathy S1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年2月23日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Probing pocket depth

研究概览

简要总结

The study titled evaluation of the efficacy of calcium phosphosilicate bioactive glass in combination with autologous platelet rich fibrin in the treatment of horizontal bone defects in periodontitis will be conducted in Vydehi Institute of Dental Sciences and Research Centre for a study period of 9 months. Periodontitis is a chronic inflammatory disease that causes loss of tooth attachment apparatus. one of the prominent signs of destructive periodontal disease is loss of alveolar bone support. In this loss of alveolar bone support horizontal bone loss is the most prominent. though the prevelance of horizontal bone loss is 92%, the available treatment modalities are only 2%. Thus the main aim of my study is evaluate the effect calcium phsphosilicate bioactive glass in combination with autologous platelet rich fibrin in the treatment of horizontal bone loss.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
30.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients diagnosed with stage II and III periodontitis according to 2017 World Workshop on the Classification of Periodontal and Peri-implant diseases and conditions Premolars and molars with a probing depth of ≥ 5mm to 8mm and a horizontal bone loss of 5mm or more from the CEJ to the alveolar crest in CBCT.

排除标准

  • Medically compromised patients Teeth with grade III mobility Patients who underwent periodontal surgery in the past one year Smokers Pregnant and lactating women.

结局指标

主要结局

Probing pocket depth

时间窗: 9 months

Clinical attachment level

时间窗: 9 months

Height of bone assessed from CEJ to the alveolar crest obtained through Cone Beam Computed Tomography radiographic method

时间窗: 9 months

Width of the bone at the thinnest portion between the buccal / lingual and palatal plate in axial tomogram

时间窗: 9 months

次要结局

  • Plaque index(Gingival index)

研究者

发起方
Dr Swathy S
申办方类型
Other [individual]

研究点 (1)

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