Comparison of Quality of Recovery (QoR)-15 Scores According to the Use of Anesthetics During General Anesthesia in the Cervical Spine Surgery Patients: Sevoflurane vs. Remimazolam
Overview
- Phase
- Not Applicable
- Intervention
- Sevoflurane based inhalation anesthesia
- Conditions
- Anterior Cervical Discectomy and Fusion (ACDF) Surgery
- Sponsor
- Gangnam Severance Hospital
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- The difference between two groups (sevoflurane vs. remimazolam) in QoR-15 scores
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperative nausea/vomiting and malignant hyperthermia. However, it is still not enough to explain which is better between TIVA or inhalation anesthesia. In particular, there is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA with remimazolam. The hypothesis of the investigators study is that, in patients with cervical spine surgery, total intravenous anesthesia based on remimazolam can improve the the quality of recovery compared to inhalation anesthesia based on sevoflurane.
Investigators
Myoung Hwa Kim
Associate Professor
Gangnam Severance Hospital
Eligibility Criteria
Inclusion Criteria
- •Adult patients who aged 20-70 years
- •ASA-PS: 1-3
- •BMI \< 30
- •Anterior cervical discectomy and fusion surgery
Exclusion Criteria
- •Tolerance or hypersensitivity to benzodiazepine
- •Dependence or addiction to psychotropic drugs or alcohol
- •Pregnant women, subjects who lack the ability to make decisions and susceptible to voluntary participation decisions
Arms & Interventions
Arm 1) Sevoflurane group
Sevoflurane based inhalation anesthesia
Intervention: Sevoflurane based inhalation anesthesia
Arm 2) Remimazolam group
Remimazolam based total intravenous anesthesia
Intervention: Remimazolam based total intravenous anesthesia
Outcomes
Primary Outcomes
The difference between two groups (sevoflurane vs. remimazolam) in QoR-15 scores
Time Frame: postoperative day 1
The difference of scores in the Quality of Recovery (QoR)-15 survey on POD 1 Total 0-150, 0 (minimum), 150 (maximum), Higher scores means better.