Glycemic Index of Table Grape Varietals

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT03248609
• Lead Sponsor: University of California, Davis

Brief Summary

Investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals or grape juice, compared to a standard amount of glucose.

Detailed Description

The study aims to investigate the postprandial glycemic responses of healthy individuals when consuming commercially available table grape varietals, compared to a standard amount of glucose. The study also aims to evaluate a new grape varietal, compared to other common table grapes, with regard to glycemic index and metabolic response related to inflammation.

Study Timeline

• Study Start: 2017-07-31
• Study First Submitted: 2017-08-09
• Study First Submitted QC: 2017-08-09
• Study First Posted: 2017-08-14
• Primary Completion: 2018-06-04
• Study Completion: 2018-06-04
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-30
• Last Update Posted: 2019-05-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Healthy men and women
• 21-75 years of age
• BMI range 20-35

Exclusion Criteria

• adults unable to consent, individuals who are not yet adults (children), pregnant women, and prisoners.
• BMI of >35 or morbid obesity.
• Diagnosed type 1 or 2 diabetes, fasting blood glucose of >125 mg/dl, or reported use of medications or supplements known to affect glucose metabolism (insulin, sulfonylureas, metformin, glucosidase inhibitors, thiazolidinedione, insulin sensitizers, GLP-1 mimetics).
• Medications known to affect gastrointestinal motility (prokinetic agents such as reglan).
• Renal, liver, pancreatic or cardiovascular disease, uncontrolled hypertension of > 160/90, inflammatory bowel disease, disorders of esophageal and gastrointestinal motility, previous gastric resection or restriction procedures, autoimmune or immunologic disorders, anemia, breastfeeding women
• Food allergy to grapes, or inability to tolerate gluten (celiac disease).
• Poor venous access.
• Smoking, illicit drug use, consuming >7 alcoholic drinks per week.
• Weight gain or loss of > 5 kg within the prior 6 months.
• Unwillingness to adhere to study protocol.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Glycemic Index	3 hours	The post-prandial glucose and insulin responses in healthy individuals to glucose containing foods or beverages.

Trial Locations

Locations (1)

University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility); 🇺🇸 Davis, California, United States