Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults
- Conditions
- Glycemic ResponseAppetitive Behavior
- Registration Number
- NCT03409497
- Lead Sponsor
- Purdue University
- Brief Summary
Assess the impact of 100% grape juice with a meal on postprandial glycemic response and subsequent appetite, food intake and cognitive function.
- Detailed Description
Investigators earlier studies and published literature suggest that the phenolic content and strong flavor intensity of 100% Concord grape juice hold potential beneficial effects on blood sugar levels. Investigators aim to better understand the consumption of 100% grape juice with a meal modifies appetite and glycemia acutely and over the day using a 24 hour glucose monitor.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- BMI between 25.0-34.9 kg/m2
- Willingness to eat all test foods
- Low consumer of tea and coffee, willingness to refrain from both during the 48 hours prior to test days and on the test day
- Fasting blood glucose below 6.1mmol/l via capillary finger-stick blood sample using a SureStep glucometer (Lifescan, Milpitas, CA)
- Taking medications known to affect glycemia, lipid metabolism or appetite
- Body weight fluctuation of >5kg in the past 3 months
- Taking vitamin or other supplements
- Smokers
- Acute or Chronic disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method change in blood glucose over 24 hours 24 hours samples taken every 5 minutes for 24 hours by a continuous glucose monitor
- Secondary Outcome Measures
Name Time Method Appetite 24 hours Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on same day as grape juice intervention
Trial Locations
- Locations (1)
Purdue University
🇺🇸West Lafayette, Indiana, United States
Purdue University🇺🇸West Lafayette, Indiana, United States