The Efficacy of Perioperative Intravenous Acetaminophen for Off-pump CABG

Phase 3

Recruiting

• Conditions: angina pectoris, old/subacute myocardial infarction, post operative pain

• Registration Number: JPRN-UMIN000015653
• Lead Sponsor: IMS Katsushika Heart Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-11
• Study Completion: 2015-11-22
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Fraility scale>=5 Disability of expressing pain Patients of converting the surgery to on-pump coronary artery bypass grafting surgeries Patients using intra-aortic balloon pumping or extracorporeal membrane oxygenation devises The nutritionally-depleted patient: body mass index<18.5 or serum albumin level<3.5g/dl Patients with liver disease: chronic virus hepatitis, alcoholic hepatitis, chronic cirrhosis Preoperative blood abnormal value of AST(aspartate aminotransferase)>=120U/l, ALT(alanine aminotransferase)>=135U/l, total bilirubin>=2.4mg/dl Hemodialysis patients Impaired renal function: serum creatinine level>=3.0mg/dl Patients with aspirin-induced asthma Patients who are taking vitamin K antagonist, isoniazid, carbamazepine, phenobarbital, phenytoin, primidone, rifampicin Patients with the allergy to acetaminophen

Study & Design

• Study Type: Interventional
• Study Design: Not specified