Sexual Dysfunction in Partner of Patients With Ankylosing Spondylitis

• Conditions: Ankylosing Spondylitis; Sexual Dysfunction
• Interventions: Other: Sexual dysfunction

• Registration Number: NCT04411485
• Lead Sponsor: Antalya Training and Research Hospital

Brief Summary

The adverse effects of rheumatologic diseases, especially Ankylosing Spondylitis (AS), on sexual functions are known. The causes of sexual dysfunction in rheumatologic diseases are due to factors such as pain, weakness, fatigue, stiffness, functional disability, anxiety, depression, hormonal deficiency, drug use, decreased libido and poor body image. Depending on these factors, sexual intercourse and frequency of sexual intercourse may decrease. Sexual dysfunction may be seen in AS due to physical and emotional problems caused by the disease.

Detailed Description

There are many studies in the literature that determine sexual satisfaction and sexual dysfunction in individuals with AS and compare individuals with AS to healthy individuals . In the light of these studies, the investigators thought that the sexual function of partner of individuals with AS may also be affected negatively. In the literature, no previous study examines the sexual function of partner of individuals with AS. Therefore, the aim was to determine the sexual function of partner of individuals with AS and to compare with healthly adults of the same sex.

Study Timeline

• Study Start: 2018-02-15
• Study First Submitted: 2020-05-28
• Study First Submitted QC: 2020-05-28
• Status Verified: 2020-06
• Study First Posted: 2020-06-02
• Last Update Submitted: 2020-06-02
• Last Update Posted: 2020-06-04
• Primary Completion: 2020-06-30
• Study Completion: 2020-07-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Being diagnosed with AS for individuals with AS,
• No additional disease (comorbid and psychiatric disease, hypothyroidism, hypopituitarism, hypogonadism or hyperprolactinemia)
• Having a partner (relationship status in a monogamous sexual relationship),
• Not smoking and drinking,
• Non-AS partner have not been diagnosed with AS and their partner is AS.

Exclusion Criteria

• Overweight or obesity (BMI <28 kg / m2)
• Having had a pelvic injury, urological or gynecological operation in the last 3 months
• Hypogonadism; penile abnormalities such as hypospadias, congenital curvature or Peyronie's disease with preserved penis stiffness
• Prostatic disorder
• Use of drugs that may affect erectile function (steroids, antihistamines, ß-blockers or SSRIs)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group of Ankylosing Spondylitis	Sexual dysfunction	Patient with ankylosing spondylitis diagnosed by a rheumatologist
Group of control	Sexual dysfunction	Healthy volunteers of the same age and gender as patients

Primary Outcome Measures

Name	Time	Method
Female Sexual Function Scale	1 week	It is a Likert-type scale that evaluates sexual dysfunction in women consisting of 19 items. The validity and reliability study of FSFI was performed by Rosen et al. (8). The scale consists of six items: desire, arousal, lubrication, orgasm, sexual satisfaction and pain. Each title is scored between 0 or 1 to 6. The lowest score is two (2) and the highest score is thirty-six (36). A higher score means better function. Rosen et al. (2000) in their study of functional status; The FSFI score was classified as good if\> 30, moderate between 23-29, and poor if \<23 .
International Erectile Function Form	1 week	The questionnaire, which consists of 15 questions in total, determines the participants' erectile function, orgasmic function, sexual desire, sexual satisfaction and overall satisfaction and these 5 different sexual function areas are scored according to the answers received. It is a Likert type scale. As the score increases, it means that each area is good.

Trial Locations

Locations (1)

Antalya Tarining and Research Hospital Ethics Commitee; 🇹🇷 Antalya, Turkey