To Study The Effect Of Magnesium Sulphate Nebulisation And Ketamine Nebulisation In Prevention Of Post-Operative Sore Throat Following I-gel Insertion For General Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- prevention of post operative sore throat following use of I-gel after magnesium sulphate nebulisation or ketamine nebulization
研究概览
简要总结
Post operative sore throat is a common complaint in patients receiving general anaesthesia to undergo surgical procedures over the years.
Irritation and inflammation of the airway is considered the most common cause of post operative sore throat.
Magnesium sulphate and Ketamine is a NMDA antagonist with anti inflammatory property which work on peripheral nerve endings in pharyngeal mucosa and can reduce the incidence of post operative sore throat.
This study is intended to evaluate and assess the incidence and severity of post operative sore throat following administration of magnesium sulphate and ketamine to the patients 15 minutes pre-operatively.
Incidence and severity of post operative sore throat will be graded on verbal rating scale post-operatively along with the assessment of any undesirable side effects following usage of supraglottic airway device I-gel to maintain anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients posted for elective surgeries and with ASA PS class 1 and 2.
排除标准
- •patient refusal patient with history of frequent sore throat and asthma oral surgeries chronic obstructive pulmonary disease head and neck surgeries mallampatti grade 3 and above, known allergies to study drug.
结局指标
主要结局
prevention of post operative sore throat following use of I-gel after magnesium sulphate nebulisation or ketamine nebulization
时间窗: Sore throat will assessed at 0th hour, 2nd hour, 4th hour and 24th hour
次要结局
- To assess hemodynamic changes (blood pressure and pulse rate) after nebulization intraoperative(Assessed at 0th, 5,10,15,20,25,30,35,40,45,50,60th minutes after the start of surgery)