Ghrelin, Growth Hormone and Growth Factors at High Altitude

Completed

• Conditions: Healthy; Growth Hormone
• Interventions: Other: exposure to high altitude

• Registration Number: NCT00966134
• Lead Sponsor: Medical University of Vienna

Brief Summary

Regulation of ghrelin, growth hormone and growth factors at high altitude and their change during ascent to high altitude has not been studied in depth yet. The study includes 33 volunteers (12f) investigated at sea level, 4 days after ascent to 3440m and 14 days after ascent to 5400-5900m.

The investigators hypothesized that during ascent growth hormone levels would increase to compensate for the higher energy needs at high altitude.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-04
• Study Completion: 2005-09
• Status Verified: 2009-08
• Study First Submitted: 2009-08-24
• Study First Submitted QC: 2009-08-25
• Study First Posted: 2009-08-26
• Last Update Submitted: 2010-02-22
• Last Update Posted: 2010-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Healthy and good physical fitness

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
probands	exposure to high altitude	-

Primary Outcome Measures

Name	Time	Method
Ghrelin, growth hormone, insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP1), IGF binding protein 2 (IGFBP2), IGF binding protein 3 (IGFBP3), acid-labile subunit (ALS), insulin, prolactin	14 days