Effect of Increased Protein Intake on Colonic Metabolism

Not Applicable

Completed

• Conditions: Protein Fermentation; Toxicity in the Colon
• Interventions: Dietary Supplement: High protein intake; Dietary Supplement: Low Protein intake

• Registration Number: NCT01280513
• Lead Sponsor: KU Leuven

Brief Summary

The purpose of this study is to modulate the protein fermentation and to investigate the effect on colon toxicity.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10
• Primary Completion: 2010-06
• Study First Submitted: 2011-01-19
• Study First Submitted QC: 2011-01-19
• Study First Posted: 2011-01-20
• Status Verified: 2012-08
• Last Update Submitted: 2012-08-01
• Last Update Posted: 2012-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Healthy
• Regular eating pattern (3 meals/day)
• Age between 18 and 45 years old
• BMI between 18,5 and 30 kg/m²

Exclusion Criteria

• Intake of antibiotics in the last month before the study
• Abdominal surgeries in the past (accept appendectomy)
• Consulting a dietician/following a diet
• Vegetarian
• Intake of pre- and/or probiotics
• Exposure to radioactivity in the year proceeding the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
High Protein intake	High protein intake	-
Low Protein intake	Low Protein intake	-

Primary Outcome Measures

Name	Time	Method
Fecal water toxicity	Participants were followed for 5 weeks, with measurements on 3 specific time points

Trial Locations

Locations (1)

KULeuven; 🇧🇪 Leuven, Vlaams-Brabant, Belgium