Diagnostic Importance of the Circulating Human Leucine-rich α-2-glycoprotein Analysed From Blood and Saliva in Children With Acute Appendicitis
试验速览
- 阶段
- 不适用
- 发起方
- KBC Split
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Level of LGR1 protein in blood
研究概览
简要总结
Acute appendicitis is a common and potentially serious medical condition which can be difficult to diagnose, especially in pediatric patients. To help recognize patients with acute appendicitis, number of laboratory and radiological test are used. Previous research has shown that Circulating Human Leucine-rich α-2-glycoprotein (LGR1) in the blood can be elevated in pediatric patients with acute appendicitis. The aim of this research is to analyse whether LGR1 levels in saliva can be used as a less invasive diagnostic method in pediatric patients with suspected acute appendicitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children with age from 5 do 17 with acute abdominal pain
- •children with clinical signs of appendicitis
排除标准
- •previous diagnosis of chronic and/or malignant disease
- •children which had previous abdominal surgery
- •pregnancy
结局指标
主要结局
Level of LGR1 protein in blood
时间窗: 72 hours
Levels of LGR1 protein in blood and saliva as measured by ELISA test
Level of LGR1 protein saliva
时间窗: 72 hours
Levels of LGR1 protein in saliva as measured by ELISA test
次要结局
未报告次要终点