A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With Timolol Hemihydrate 0.5% Solution Once or Twice Daily Versus Timolol Maleate in Sorbate
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 103
- 试验地点
- 1
- 主要终点
- Subject Reported Burning/Stinging
研究概览
简要总结
The objective of the study was to evaluate whether timolol hemihydrate is more comfortable upon instillation than timolol maleate in sorbate. This was an observational study. Subjects with open-angle glaucoma or ocular hypertension were asked to complete a survey regarding their normal treatment. No treatment was prescribed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •willing to comply with investigator's and protocol's instructions
- •patients signature on the informed consent document
- •open-angle glaucoma or ocular hypertension
- •currently prescribed timolol hemihydrate (once a day (QD) or twice a day (BID))or timolol maleate in sorbate QD as monotherapy or as a part of 2-drug therapy in at least one eye
排除标准
- •inability to understand the trial procedures
- •inability to give informed consent
- •inability to understand, read, or write English
- •best corrected visual acuity of 20/200 or worse in each eye
- •current moderate to severe infectious or inflammatory condition of the eye or eyelids including
- •current moderate to severe dry eye syndrome
- •current chronic use of ocular corticosteroids, ocular surgery or intraocular laser surgery to either eye in the prior 3 months
- •treated with 3 or more glaucoma medicines in both eye
研究组 & 干预措施
Timolol hemihydrate
Subjects currently prescribed timolol hemihydrate 0.5% solution.
干预措施: timolol hemihydrate (Drug)
Timolol maleate
Subjects currently prescribed timolol maleate in sorbate.
干预措施: timolol maleate (Drug)
结局指标
主要结局
Subject Reported Burning/Stinging
时间窗: Upon instillation
Subjects reported burning/stinging after they put the drops in their eyes using the following scale: 0=never, 1=rarely, 2=sometimes, 3=frequently, 4=always.
Subject Reported Tearing
时间窗: Upon instillation.
Subjects reported tearing after they put the drops in their eyes using the following scale:0=never, 1=rarely, 2=sometimes, 3=frequently, 4=always.
Subject Reported Light Sensitivity
时间窗: Upon instillation
Subjects reported light hurt their eyes after they put the drops in their eyes using the following scale: 0=never, 1=rarely, 2=sometimes, 3=frequently, 4=always.
Subject Reported Blurred Vision
时间窗: Upon instillation
Subjects reported their vision was blurred after they put the drops in their eyes using the following scale: 0=never, 1=rarely, 2=sometimes, 3=frequently, 4=always.
次要结局
未报告次要终点