Postoperative Hemodynamic Effects of Cardiac Resynchronisation Therapy in Cardiac Surgery Patients with Impaired Left Ventricular Functio

Completed

• Conditions: Biventricular pacing; Resynchronisation Therapy; 10019280

• Registration Number: NL-OMON31347
• Lead Sponsor: Catharina-ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

• Age of 18 years or more.
• Patients scheduled for coronary artery bypass grafting surgery (CABG) and/or valve surgery.
• Left ventricular ejection fraction (EF) of 35% or less.
• Sinus rhythm with one of the following criteria:
1. QRS duration of > 130 ms and left bundle branch pattern
2. Pacemaker dependent patients with right ventricular paced rhythm and QRS width of > 180 ms, or
3. Evidence of left ventricular dyssynchrony with Tissue Doppler Imaging (TDI)
• Able to give informed consent.

Exclusion Criteria

Myocardial infarction within the past 3 months

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in left ventricular pressures after biventricular pacing in comparison<br /><br>with the patient*s own rhythm and right ventricular pacing. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Perioperative changes in hemodynamic performance and need for mechanical and<br /><br>pharmacological support after biventricular pacing.</p><br>