Effects of a low versus moderate intense physical Activity program oN IMmune recovery during pediatric ALlo-HSCT

Not Applicable

• Conditions: C95.0; C81-C96; Acute leukaemia of unspecified cell type; Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

• Registration Number: DRKS00019865
• Lead Sponsor: niversitätsklinikum Essen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

Maligne onco-hematologigal disease; assigned for an allo-HSCT in Essen; signed informed consent

Exclusion Criteria

Other malignant or benign disease; contraindication for physical exercise assigned by the oncologist and inability to follow training protocol for experimental or control intervention

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quantity of NK cells and NK cell subsets at day +30

Secondary Outcome Measures

Name	Time	Method
-Laboratory Parameters such as leukocytes, neutrophils, ILCs, NK-cells at day +15, +30, discharge, +45, +60, +75, +100 <br>-Physiological Performance and Motor skills such as Maximum isometric leg Extension, Maximum isometric leg Extension, Sit to stand 5 rep, Single leg stance, Aerobic capacity at day -3, +30, discharge, +100<br>-Psychological Parameters such as Fatigue, Quality of life at day -3, +30, discharge, +100