Investigation of the effects of curcuminoids on the risk of heart disease

Phase 2

• Conditions: Condition 1: Dyslipidemia. Condition 2: Obesity.

• Registration Number: IRCT2013082914521N1
• Lead Sponsor: Mashhad University of Medical Sciences Research Council

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

obese subjects (with body mass index (BMI) = 30) who had either < 2 risk factors (except diabetes mellitus) for coronary heart disease (CHD) plus 160 mg/dL < LDL-C < 190 mg/dL, or = 2 CHD risk factors (except diabetes mellitus) and 130 mg/dL < LDL-C < 160 mg/dL. Exclusion criteria were history of systemic diseases (such as systemic lupus erythematosus, kidney disease, diabetes mellitus and established cardiovascular disease), consumption of drug supplements within the preceding 6 months and history of taking any lipid-lowering drug.

Exclusion criteria: systemic disease or history of systemic disease (such as lupus, kidney disease, diabetes mellitus); history of cardiovascular disease; BMI < 30; consumption of drug supplements within the 6 months and history of taking any lipid lowering drug.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total cholesterol. Timepoint: Baseline, week 4, week 6 and week 10. Method of measurement: Routine enzymatic methods using standard biochemistry kits on an autonalyzer.;Triglycerides. Timepoint: Baseline, week 4, week 6 and week 10. Method of measurement: Routine enzymatic methods using standard biochemistry kits on an autonalyzer.;HDL cholesterol. Timepoint: Baseline, week 4, week 6 and week 10. Method of measurement: Routine enzymatic methods using standard biochemistry kits on an autonalyzer.;LDL cholesterol. Timepoint: Baseline, week 4, week 6 and week 10. Method of measurement: Routine enzymatic methods using standard biochemistry kits on an autonalyzer.