Effect of combined of supplement with carnitine and coenzyme Q10, versus therapeutic lifestyle changes (TLC Diet) diet on myocardial infarction patients.
Not Applicable
- Conditions
- myocardial infarction.Acute myocardial infarction
- Registration Number
- IRCT2282620150719N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 128
Inclusion Criteria
inclusion criteria:
first experience of myocardial infarction;
age between 40 -65;
candidate for angioplasty revascularization;
LDL >130?
without anti lowering lipid six month ago;
ejection fraction between 30-60;
receive atorvastatin 80 mg daily;
exclusion criteria:
allergy with atorvastatin;
history of cardiac event after angioplasty;
patient with arrhythmia or congestive heart failure;
history of consumption of antioxidant such as vitamin C, E and omega 3;
history of consumption warfarin;
history of documented psychological disease ;
leave the patient before 60 days after intervention in RCT;
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method DL. Timepoint: 24 hours after myocardial infarction than 3 month after intervention. Method of measurement: enzymatic method calculate.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: 10 days after myocardiad in farction. Method of measurement: MacNew questionaire.;Ejection fraction. Timepoint: 24 houre after myocardiad in farction. Method of measurement: echocardiography by specilalist.;Triglyceride (TG). Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: Photometric method.;High-density lipoprotein (HDL). Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: Photometric method.;Physical Activity. Timepoint: 7 days before myocardial infarction then 3 month after intervention. Method of measurement: Intinternational Physical Activity Questionnaire - Short Form (IPAQ-SF).;H- CRP. Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: ELISA by micropipette reader.;IL-6. Timepoint: 24 houre after myocardiad in farction and 3 mouth after intervention. Method of measurement: ELISA.