Genetic Basis of Pacing-induced Cardiomyopathy

Completed

• Conditions: Cardiomyopathies; Pacemaker, Artificial

• Registration Number: NCT03317964
• Lead Sponsor: The Guthrie Clinic

Brief Summary

The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.

Detailed Description

DNA will be extracted from the saliva to test for changes in genes related to cardiomyopathy.

Study Timeline

• Study Start: 2017-10-16
• Study First Submitted: 2017-10-16
• Study First Submitted QC: 2017-10-18
• Study First Posted: 2017-10-23
• Status Verified: 2025-06
• Primary Completion: 2025-06-19
• Study Completion: 2025-06-19
• Last Update Submitted: 2025-06-19
• Last Update Posted: 2025-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 153

Inclusion Criteria

• Patients who have been assessed for cardiomyopathy

Exclusion Criteria

• Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of participants with genotype frequency	through study completion, an average of 1 year	Number of participants with genotype frequency based on genetic testing of saliva samples

Trial Locations

Locations (1)

Robert Packer Hospital; 🇺🇸 Sayre, Pennsylvania, United States