Periodontal treatment for improving glycaemic control in diabetic patients

Not Applicable

Completed

• Conditions: Diabetes mellitus, periodontal disease; Nutritional, Metabolic, Endocrine; Unspecified diabetes mellitus

• Registration Number: ISRCTN15334496
• Lead Sponsor: niversity Hospital of Toulouse (CHU de Toulouse) (France)

Brief Summary

2009 results in: https://www.ncbi.nlm.nih.gov/pubmed/19646281 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30136741 (added 30/10/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-04-30
• Study Completion: 2010-12-31
• Last Update Posted: 25 November 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

1. Male or female, aged >= 18 year old
2. Diabetes mellitus (type I or II), diagnosed since at least one year
3. HbA1c levels comprised between 7.0 and 9.5%
4. No change in diabetic medication 3 months before inclusion
5. Periodontal disease (at least one site on at least 4 teeth with Probing Pocket Depth >= 4 mm AND Clinical Attachment Loss >= 3 mm)
6. At least 6 remaining teeth
7. Subject able to understand and willing to provide written informed consent in French
8. Subject affiliated to the security system

Exclusion Criteria

1. Receiving antibiotherapy or chronic steroid therapy
2. Presence of significant renal disease, as indicated by creatinine clearance less than 60 ml/min
3. Have another medical condition likely to cause hospitalisation within 4 months
4. Presence of serious or unstable infectious disease, hepatic disease, phenylcetonuria
5. Subject at risk of endocarditis
6. Pacemaker
7. Antithrombotic treatment
8. History of allergy to amoxicillin and clindamycin
9. Pregnant, lactating, or plans to become pregnant during the study
10. Participation in another study with an investigational compound

Study & Design

• Study Type: Interventional
• Study Design: Not specified